Incidence and Prognostic Implication of Bone Marrow Involvement in Hodgkin’s Lymphoma

  • Rimpi Bansal Department of Pathology, Gian Sagar Medical College And Hospital, Punjab. India
  • Puneet Kaur Department of Pathology, Gian Sagar Medical College And Hospital, Punjab. India
  • Jatin Sarin CCDC, Chandigarh, India
  • Anureet Kaur Department of Pathology, Gian Sagar Medical College And Hospital, Punjab. India
  • Akshita Sarin Government Medical College and hospital, Chandigarh India
Keywords: Hodgkin’s Lymphoma, RS cells, Bone Marrow biopsy

Abstract

Introduction- : Conducting Bone marrow examination in a Hodgkin's Lymphoma (HL) patient  at the time of diagnosis is done routinely to determine the stage of the disease. The aim of this study was to analyze the incidence and prognosis of bone marrow involvement in patients with Hodgkins lymphoma, retrospectively.  Materials and Patients: Ten patients of Hodgkins lymphoma were incorporated in the current study. Bone marrow aspiration and biopsy was done in all ten cases as part of staging procedure. Results: Three patients showed involvement of bone marrow by Hodgkin’s lymphoma and both the patients had clinically poor outcome. Discussion and Conclusion: Bone marrow examination is important in stage II and III of Hodgkin”s lymphoma because positive result will upstage the disease. Also, bone marrow involvement indicates an aggressive disease and poor prognosis for the patient.

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Published
2021-12-02
Section
Original Article