Glomeruli Sparing Pattern of Unclassified Renal Cell Carcinoma: A Rare Neoplasm
AbstractUnclassified renal cell carcinoma (URCC), an aggressive form of renal cell carcinoma (RCC), represents 0.7– 5 .7% of renal tumours. Glomerular sparing in renal neoplasms (GS) is defined as a unique growth pattern in which tumour cells overrun intact glomeruli. An elderly woman presented with symptoms of left flank pain for three months along with fullness in the abdomen. On clinical and radiological examination, a renal mass was revealed and operated upon. A diagnosis of URCC with a glomerular sparing pattern was made on histopathological examination. The pathological details of this rare neoplasm are presented in this article.
Chander B, Preet K, Bharti R, Deb P. Renal cell carcinoma, unclassified with unique features. J Cancer Res Ther. 2015;11(4):1027.
Moch H., Humphrey PA, Ulbright TM, Reuter V. WHO Classification of Tumours of the Urinary System and Male Genital Organs (4th edition). Lyon, France: International Agency for Research on Cancer; 2016.
Eble J N, Sauter G, Epstein J I, Sesterhenn I A. WHO classifications of tumor. Pathology and Genetics of Tumors of the Urinary System and Male Genital Organs. Lyon, France: International Agency for Research on Cancer Press; 2004.
Ronny FMH, Sarungbam J, Zhong X, Yusuf Y, Yang X, Zhong M. Glomerular sparing pattern in primary kidney neoplasms: clinical, morphological and immunohistochemical study. Am J Clin Exp Urol. 2014;2(1):76–81.
Lopez-Beltran A, Kirkali Z, Montironi R, Blanca A, Algaba F, Scarpelli M, et al. Unclassified renal cell carcinoma: a report of 56 cases: UNCLASSIFIED RCC. BJU Int. 2012;110(6):786–93.
Truong LD, Shen SS. Immunohistochemical diagnosis of renal neoplasms. Arch Pathol Lab Med. 2011;135(1):92-109.
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