Fungal Infection of Paranasal Sinus After COVID-19 Infection: A Tale of Two Fungi

  • Sunayana Mukesh Jangla Microbiology Section, Department of Pathology, Bhabha Atomic Research Centre Hospital, Anushakti Nagar, Trombay, Mumbai 400-094, Maharashtra, India
  • Atul Shivaji Wadawkar Nucleus The Diagnostic Centre, “Rose” Flower Valley, Khadakpada Circle, Khadakpada, Kalyan (W), Maharashtra 421301, India
  • Aniruddha Jayavant Randive Nucleus The Diagnostic Centre, “Rose” Flower Valley, Khadakpada Circle, Khadakpada, Kalyan (W), Maharashtra 421301, India
  • Sandip Sakharam Sakpal Nucleus The Diagnostic Centre, “Rose” Flower Valley, Khadakpada Circle, Khadakpada, Kalyan (W), Maharashtra 421301, India
Keywords: Aspergillus, COVID-19, immunocompromised, infection, Mucor, sinus

Abstract

Coronavirus disease (COVID-19) is an infection caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Many twists and turns have occurred regarding its various aspects since the time it was first detected especially medical management. The COVID-19 symptom array has been ever expanding and recently secondary fungal infection has emerged as a top-up to the trouble. Post COVID-19 secondary fungal infections caused by Mucor have recently emerged as a cause of concern. However, infection caused by a combination of two fungal moulds from a site barring the lungs as a sequalae to the coronavirus disease comes as a surprise.

References

Dikid T, Chaudhary S, Goel K, Padda P, Sahu R. Responding to COVID-19 pandemic: Why a strong health system is required. Indian J Med Res 2020; 151:140-5

Sharna S, Grover M, Bhargava S, Samdani S, Kataria T. Post coronavirus disease mucormycosis: a deadly addition to the pandemic spectrum. J Laryngol Otol 2021;1-6.

Dallalzadeh O L, Ozzello J D, Liu Y C, Kikkawa O D, Korn S B. Secondary infection with rhino-orbital cerebral mucormycosis associated with COVID-19. Orbit 2021;23;1-4

Limon J J, Skalski H J, Underhill M D, Commensal fungi in Health and Disease. Cell Host Microbe 2017;9;22(2):156-165

Chander J. A Textbook of Mycology 2nd New Delhi : Mehta Publishers ;2002:p. 286-299

Lai Chih-Cheng, Yu Weng-liang.COVID-19 associated with pulmonary aspergillosis: A literature review.J Microbiol Immunol Infect 2021 Feb ;54(1):46-53.

Hai-Yan Fu, Yu Luo, Jian-Peng Gao, Lin Wang, Hong-Juan Li, Xiang Li, Lian Xue et al. Effects of Short-Term Low-Dose Glucocorticoids for Patients with Mild COVID-19. BioMed Res Intl, vol. 2020, Article ID 2854186,

Sarkar S, Gokhale T, Choudhary SS, Deb AK. COVID-19 and orbital mucormycosis. Indian J Opthalmol 2021;69:1002-4.

Soman R, Sunavala A. Post COVID-19 Mucormycosis -from the Frying Pan into the Fire. Macleods 2021;69

Hamid M, Ahmed Sitt, Jamii Abdulmoneim, Al-Qahatani Ali. Allergic Fungal Rhinosinusistis Caused by Aspergillus flavus. Annals of African Surgery 2019 Aug;16(1):75-77.

Chen Chien-Yuan, Sheng Wang-Huei, Cheng Aristine, Chen Yee-Chun, Tsay Woei, Tang Jih-Luh et al. Invasive fungal sinusitis in patients with hematological malignancy: 15 years experience in a single university hospital in Taiwan. BMC Infect Dis 2011 Sep; 11:250

Sen M, Lahane S, Lahane P T,Parekh R,Honavar G S.Mucor in a Viral Land: A Tale of Two Pathogens. Indian J Opthalmol 2021;69(2):255-252

Singh V. Fungal rhinosinusitis: Unravelling the disease spectrum. J Maxillofac Oral Surg 2019; 18(2):164-179

Published
2021-08-30
Section
Case Report