Disseminated Histoplasmosis in a Retropositive Young Male: A Case Report

  • Aniya Antony Department of Pathology, Amala Institute of Medical Sciences
  • Sreeja Raju Department of Pathology, Amala Institute of Medical Sciences http://orcid.org/0000-0003-1220-9226
  • Vanessa John T Department of Pathology, Amala Institute of Medical Sciences
  • Edwin George Department of Pathology, Amala Institute of Medical Sciences
  • Joy Augustine Department of Pathology, Amala Institute of Medical Sciences
Keywords: Disseminated histoplasmosis, retropositive, FNAC, peripheral smear


Disseminated histoplasmosis is caused by the dimorphic fungus Histoplasma capsulatum. This fungal infection is commonly seen in immunocompromised patients, especially in AIDS patients, children and elderly population. Here we present a case report of a 24-year-old male who was admitted with generalised fatigue and generalised lymphadenopathy. He was found to be retropositive on evaluation and FNAC of the node surprisingly revealed Histoplasmosis. Presence of these organisms were also seen on the peripheral smear which could be picked up only on reviewing the smear again. With this case report we wish to emphasize the need for careful and diligent search of these organisms in the peripheral smear.


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Case Report