Application of IAC Yokohama System For Reporting Breast Fine Needle Aspiration- A Retrospective Study
AbstractBackground: Breast cancer is one of the most common cancers worldwide in females and is an important cause of mortality and morbidity. FNAC is a safe, reliable, sensitive, specific, time saving and cost effective procedure useful in the diagnosis of carcinoma breast. It helps the surgeon in planning the treatment, and thereby reducing the delay in treatment. The primary aim of this study is to find out the spectrum of breast lesions on fine needle aspiration cytology based on IAC Yokohama system in a tertiary care hospital of north central Haryana.Methods: This is a retrospective study carried out in a tertiary care hospital of north-central Haryana and included 417 patients of palpable breast lumps presented in the Department of Pathology for FNAC during January 2018 to December 2019. FNAC was done under all aseptic conditions and various cytomorphological patterns were analysed according to the IAC Yokohama system for reporting breast fine needle aspirations.Result: Of the 417 cases included in the study, 328 cases were benign, 04 were atypical probably benign, 04 were suspicious for malignancy, 64 cases were malignant and 17 cases were inadequate for opinion. Fibroadenoma was found to be the most common breast lesion. Overall benign breast lesions are much more common than malignant lesions. Conclusion: FNAC is a useful tool to diagnose malignant lesions of the breast and help the surgeon in differentiating benign and malignant lesions. Early diagnosis aid in effective management of malignant lesions of the breast and thereby reducing the mortality in these patients.
Siegel RL, Miller KD and Jemal A. Cancer statistics. CA: A Cancer Journal for Clinicians 2015; 65: 5–29
Ahmad N, Kalsoom S, Mahmood Z et al. Comparative evaluation of selected sex hormones in premenopausal and postmenopausal women with breast cancer. International Journal of Biosciences(IJB) 2019; 15: 10-13
Salzman B, Fleegle S, Tully AS. Common breast problems. Am Fam Physician 2012; 86: 343–49
Morris A, Pommier RF, Schmidt WA, Shih RL, Alexander PW, Vetto JT. Accurate evaluation of palpable breast masses by the triple test score. Arch Surg. 1998; 133: 930–4
Ngotho J, Githaiga J, Kaisha W. Palpable discrete breast masses in young women: two of the components of the modified triple test may be adequate. S Afr J Surg. 2013;51:58–60
Muchiri LW, Penner DW, Adwok J, Rana FS. Role of fine-needle aspiration biopsy in the diagnosis of breast lumps at the Kenyatta National Hospital. East Afr Med J. 1993; 70: 31–33
Strax P. Detection of breast cancer. Cancer 1990; 66: 1336-40
Susan C Lester. The breast. Kumar V, Abbas AK, Aster JC editors. Robbins and Cotran Pathologic basis of disease. Gurgoan: Reed Elsevier India Pvt Ltd; 2015;1043-71
Hukkinen K, Kivisaari L, Heikkila PS, et al, Unsuccessful preoperative biopsies, fine needle aspiration cytology or core needle biopsy, lead to increased costs in the diagnostic workup in breast cancer. Acta Oncol 2008; 47:1037-40.
Field AS, Raymond WA, Schmitt F. The international academy of cytology Yokohama system for reporting breast fine needle aspiration biopsy cytopathology. 1st ed. Heidelberg: Springer; 2020.
M Kumar, K Ray, S Harode, DD Wagh. The Pattern of Benign Breast Diseases in Rural Hospital in India, East and Central African Journal of Surgery 2010; 15:59-64
Adesunkanmi, A.R., E.A. Agbakwuru, . Benign breast disease at Wesley Guild Hospital, Ilesha, Nigeria. West Afr. J. Med.2001; 20: 146 -51
Chandanwale S,Rajpal M, Jadhav P, Sood S, Gupta K, Gupta N. Pattern of benign breast lesions on fnac in consecutive 100 cases: a study at tertiary care hospital in India IJPBS 2013;4:129-138
Panjvani SI, Parikh BJ, Parikh SB, Chaudhari BR, Patel KK, Gupta GS, et al. Utility of fine needle aspiration cytology in the evaluation of breast lesions. J Clin Diagn Res. 2013; 7: 2777–79.
Catherine Goehring and Alfredo Morabia.. Epidemiology of Benign Breast Disease, with Special Attention to Histologic Types. Epidemiol Rev 1997; 19: 310-327.
Malik R, Bhardwaj VK; Breast lesions in young females. A 20year study for significance of early recognition. Indian J Pathol Microbiol., 2003; 46(4): 559-62.
Jyoti Priyadarshini Shrivastava, Alok Shrivastava. “Fine Needle Aspiration Cytology of Breast Lumps with Clinical and Histopathological Correlation: A 2 Year Study in Gwalior, India”. Journal of Evolution of Medical and Dental Sciences 2015; 4: 9729-34
Chandanwale SS, Gupta K, Dharwadkar AA, Pal S, Buch AC, Mishra N. Pattern of palpable breast lesions on fine needle aspiration: A retrospective analysis of 902 cases. J Midlife Health. 2014; 5(4): 186–191
Predictions - Globocan – iarc globocan. iarc. fr/ Pages/ burden_sel.aspx
Pradhan M, Dhakal HP. Study of breast lumps of 2,246 cases by fine needle aspiration. J Nepal Med Assoc 2008; 47: 205-9
Mayun AA, Pindiga UH, Babayo UD. Pattern of histopathological diagnosis of breast lesions in Gombe, Nigeria. Niger J Med 2008; 17: 159-62
Khan S, Kapoor AK, Khan IU, et al. Prospective study of pattern of breast diseases at epalgunj medical college (NGMC). Nepal Kathmandu Univ Med J 2003; 1: 95-100
Balkrishna B Yeole, AP Kurkure. An epidemiological assessment of increasing incidence and trends in breast cancer in Mumbai and other sites in India during the last two decades. Asian Pacific Journal of Cancer Prevention, 2003; 4: 51-56
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access at http://opcit.eprints.org/oacitation-biblio.html).