Osseocartilaginous metaplasia in the Endometrium: A Rare Reversible Cause of Secondary Infertility
AbstractOsteo-cartilaginous metaplasia in endometrium is an infrequent finding and usually presents with secondary infertility. This is a benign entity and usually associated with a previous history of abortion. It can be treated successfully with hysteroscopy and henceforth reverting infertility. Awareness of this entity is important in order to avoid overdiagnosis of mixed Mullerian tumor of the endometrium followed by hysterectomy. Herein, we present one such case of a 28-year-old female who presented with secondary infertility.
Patil S, More S, Narchal S. Endometrial cartilaginous metaplasia: A case report with literature review. Journal of Mid-life Health. 2013;4(3):195.
Nicolae A, Preda O, Nogales F. Endometrial metaplasias and reactive changes: a spectrum of altered differentiation. Journal of Clinical Pathology. 2010;64(2):97-106.
Ip P. Benign endometrial proliferations mimicking malignancies: a review of problematic entities in small biopsy specimens. Virchows Archiv. 2018;472(6):907-917.
Cayuela E, Perez-Medina T, Vilanova J, Alejo M, Cañadas P. True osseous metaplasia of the endometrium: the bone is not from a fetus. Fertility and Sterility. 2009;91(4): 1293.e1-1293.e4.
Acharya U, Pinion S, Parkin D, Hamilton M. Osseous metaplasia of the endometrium treated by hysteroscopic resection. BJOG: An International Journal of Obstetrics & Gynaecology. 1993;100(4):391-392.
Sethi S, Bhatnagar S, Sethi S. Heterotopic chondroid tissue in the uterus. Indian Journal of Pathology and Microbiology. 2008;51(4):568.
Coccia M, Becattini C, Bracco G, Scarselli G. Ultrasound-guided hysteroscopic management of endometrial osseous metaplasia. Ultrasound in Obstetrics and Gynecology. 1996;8(2):134-136.
Shimizu M, Nakayama M. Endometrial ossification in a postmenopausal woman. Journal of Clinical Pathology. 1997;50(2):171-172.
Hsu C. Endometrial Ossification. BJOG: An International Journal of Obstetrics and Gynaecology. 1975;82(10):836-839.
Dutt S. Endometrial Ossification Associated with Secondary Infertility. Case Report. Bjog: An International Journal of Obstetrics and Gynaecology. 1978;85(10):787-789.
Lee J, Lee H, Kwon H, Na S, Hwang J, Lee D. A case of endometrial osseous metaplasia treated by hysteroscopic operation. Korean Journal of Obstetrics & Gynecology. 2012;55(5):361.
Shah N, Kale K, Shah V. Osseous metaplasia of endometrium: a rare cause of secondary infertility. International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 2016;532-535.
Bahceci M, Demirel L. Case report: Osseous metaplasia of the endometrium: a rare cause of infertility and its hysteroscopic management. Human Reproduction. 1996;11(11):2537-2539.
Copyright (c) 2022 Swagatika Senapati, Shruti Mahawar, Krushna Chandra Pani
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access at http://opcit.eprints.org/oacitation-biblio.html).