Myeloid Sarcoma presenting as orbital mass: a diagnostic challenge

  • Supriyo Roy Chaudhury Medical College, Kolkata. West Bengal
  • Bhawna Bhutoria Jain Medical College, Kolkata. West Bengal
  • Chetan Jain Medical College, Kolkata. West Bengal
  • Sarbani Chattopadhyay Medical College, Kolkata, West Bengal
Keywords: Orbit, Myeloid Sarcoma, Cytology, Histology, Immunohistochemistry


Myeloid sarcomas (MS) are extramedullary myeloid neoplasm and can present as solitary tumor without bone marrow and blood involvement.The rarity of the condition, its atypical presentation & difficulty to diagnose it in routine histopathological sections pose a diagnostic challenge to both pathologists and clinicians which prompted us to present this case.A case of myeloid sarcoma occurring as orbital mass in a 60 year old is presented here. The finding as seen on a cytological smear, histological features and immunohistochemistry is discussed.Strong clinical suspicion is prerequisite. The pathologist should examine the slide carefully so that the diagnosis is not missed. Presence of eosinophilic myelocyte provides a diagnostic clue.

Author Biographies

Supriyo Roy Chaudhury, Medical College, Kolkata. West Bengal
Department Of PathologyAssistant Professor
Bhawna Bhutoria Jain, Medical College, Kolkata. West Bengal
Department Of PathologyAssociate Professor
Chetan Jain, Medical College, Kolkata. West Bengal
Department Of PathologyPost Graduate Trainee
Sarbani Chattopadhyay, Medical College, Kolkata, West Bengal
Department of PathologyProfessor and Head


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Case Report