Rosai Dorfman Disease of Kidney: Report of a Rare Case

  • Pritika Kushwaha Department of Pathology, Rani Durgavati Medical College, Banda, India
  • Bembem Khuraijam Department of Pathology, Maulana Azad Medical College, New Delhi, India
  • Nita Khurana Department of Pathology, Maulana Azad Medical College, New Delhi, India
  • Anubhav Vindal Department of Surgery, Maulana Azad Medical College, New Delhi, India
Keywords: Rosai Dorfman Disease, Kidney, Histiocytosis, Renal cell carcinoma


Rosai Dorfman Disease (RDD) is a type of histiocytoses usually affecting the lymph nodes. Extranodal involvement by RDD can occur, although, infrequently. However, extranodal RDD without a prior history of the nodal variant of the disease is rare. Present case report highlights this rare occurrence. A 75 years old female presented with left renal mass with no significant previous medical or surgical history. PET-CT scan revealed two solid lobulated mass in the left kidney, suggesting Renal Cell Carcinoma. Radical nephrectomy was performed, which on histopathological examination showed features of RDD and was confirmed subsequently by immunohistochemical and special stains.


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Case Report