Water Clear Parathyroid Adenoma: A report of 2 cases

  • Subhash Yadav Consultant Pathologist Seth GS Medical College & KEM Hospital
  • Kritika Singh Seth GS Medical College, Mumbai
  • Pragati Sathe Seth GS Medical College, Mumbai
Keywords: Water clear, parathyroid adenoma

Abstract

Hyperparathyroidism occurs mainly due to parathyroid hyperplasia, adenoma and rarely carcinoma. Most of the adenomas are composed of chief cells. Water clear cell adenoma are a rare phenomenon. We are sharing two cases of parathyroid adenomas composed entirely of water clear cells and requires high degree to suspicion to identify them as they have low endocrinological activity. DOI: 10.21276/APALM.1074

References

1. Liang Y. Mojica W. Chen F Water-Clear Cell Adenoma of Parathyroid Gland: A Case Report and Literature Review: N A J Med Sci. 2010;3(4):194-198

2. Piggott R. Water P. Ashraf J. Colesky F. Kerin M.J. Water-clear cell adenoma: A rare form of hyperparathyroidism Int J Surg Case Rep. 2013; 4(10): 911–913

3. Kazuko K. Yosuke O. Takahisa T , et. Al. A rare case of primary hyperparathyroidism with clear cell adenoma: Endocrine journal 51: 207-212, 2004

4. Ezzat T, Maclean G, Parameswaran R, et al. Primary hyperparathyroidism with water clear cell content: the impact of histological diagnosis on clinical management and outcome. Annals of The Royal College of Surgeons of England. 2013;95(3):e60-e62.

5. Roth SI. The ultrastructure of primary water-clear cell hyperplasia of the parathyroid glands. Am J Pathol. 1970 Nov;61(2):233-48

6. Kuhel WI, Gonzales D, Hoda SA, Pan L, Chiu A, Giri D, DeLellis RA. Synchronous water-clear cell double parathyroid adenomas a hitherto uncharacterized entity? Arch Pathol Lab Med. 2001 Feb;125(2):256-9
Published
2017-05-29
Section
Case Report