Cytological-Radiological Correlation of Image Guided FNAC Of Hepatic Mass Lesions: Our Experience In Tertiary Care Centre
Keywords:
Hepatocellular Carcinoma, FNAC, Image Guided, Metastasis
Abstract
Background: Fine needle aspiration cytology is of latest and extensively utilized in the diagnosis of lesions aided by image guidance, it is fast becoming an initial investigation of choice for various hepatic lesions. It is safe, less traumatic, quick and cost effective tool. The present study was undertaken to know the pathological spectrum of hepatic mass lesions and to correlate the cytoradiological findings.Methods: The present study was conducted in a tertiary care centre of North India on 169 patients with hepatic lesions over a period of two years. Image guided FNAC was carried out and aspirates were examined, and compared with radiological diagnoses.Results: Metastatic malignancies were more frequent (58%) than hepatocellular carcinoma (HCC). By cytology, the most common metastases was of adenocarcinoma (49.1%) followed by squamous cell carcinoma, small cell carcinoma and poorly differentiated carcinoma, malignant melanoma and lymphoma. HCV was seen to be associated with hepatocellular carcinoma in 31.3% cases. Multiple SOLs was more common finding in radiology for HCC than single SOL. Cytoradiological correlation was found to be 92% in the present study.Conclusion: Present study thus concludes that image guided FNAC of hepatic lesions is a simple, safe, economically prudent technique associated with low morbidity and leading to quick and early diagnosis.References
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13. Kaur H, Manjari M, Thaman RG, Singh G. Prevalence of markers of Hepatitis C virus among the blood donors. J Clin Diagn Res 2012;6:959-62.
14. Wee A. Fine needle aspiration biopsy of the liver: Algorithmic approach and current issues in the diagnosis of hepatocellular carcinoma. Cytojournal 2005;2:7.
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2. Chhieng DC. Fine needle aspiration biopsy of liver - an update. World J Surg Oncol 2004;2:5.
3. Kramer H, Koeter GH, Sleijfer DT, van Putten JW, Groen HJ. Endoscopic ultrasound-guided fine-needle aspiration in patients with mediastinal abnormalities and previous extrathoracic malignancy. Eur J Cancer 2004;40:559-62.
4. Soyuer I, Ekinci C, Kaya M, Genc Y, Bahar K. Diagnosis of hepatocellular carcinoma by fine needle aspiration cytology. Cellular features. Acta Cytol 2003;47:581-9.
5. Nazir RT, Sharif MA, Iqbal M, Amin MS. Diagnostic accuracy of fine needle aspiration cytology in hepatic tumours. J Coll Physicians Surg Pak 2010;20:373-6.
6. Nasit JS, Patel V, Parikh B, Shah M, Davara K. Fine-needle aspiration cytology and biopsy in hepatic masses: A minimally invasive diagnostic approach. Clin Cancer Investig J 2013;2:132-42.
7. Rasania A, Pandey CL, Joshi N. Evaluation of FNAC in diagnosis of hepatic lesion. J Cytol 2007;24:51-4.
8. Singh S, Sen R, Kumar S, Gupta S, Chhabra S. Profile of liver fine needle aspiration in tertiary care hospital. Euroasian J Hepatogastroenterol 2013;3:31-5.
9. Ahmad SS, Akhtar K, Akhtar SS,Abari A, Nasir A, Khalid M. Ultrsound guided fine needle aspiration biopsy of abdominal masses. JK Science 2006;8:200-4.
10. Adhikari RC, Tuladhar A, Shrestha S, Sharma SK. Deep seated thoracic and abdominal lesions : usefulness of ultrasound guided fine needle aspiration cytology, a 3 year experience. Nepal Med Coll J 2010;12:20-5.
11. Swamy MCM, Arathi C, Kodandaswamy C. Value of ultrasonography-guided fine needle aspiration cytology in the investigative sequence of hepatic lesions with an emphasis on hepatocellular carcinoma. J Cytol 2011;28:178-84.
12. Sumana BS, Muniyappa B. Ultrasonography Guided Fine Needle Aspiration Cytology with Preparation of Cell Blocks in the Diagnosis of Intra-Abdominal Masses. J Clin Diag Res. 2015;9:08-12.
13. Kaur H, Manjari M, Thaman RG, Singh G. Prevalence of markers of Hepatitis C virus among the blood donors. J Clin Diagn Res 2012;6:959-62.
14. Wee A. Fine needle aspiration biopsy of the liver: Algorithmic approach and current issues in the diagnosis of hepatocellular carcinoma. Cytojournal 2005;2:7.
15. Ji XL. Fine-needle aspiration cytology of liver diseases. World J Gastroenterol 1999;5:95-7.
Published
2016-12-15
Section
Original Article
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