Prevalence of Transfusion Transmitted Infections among Blood Donors at a Tertiary care Teaching Hospital in Southern Rajasthan

  • Preeti Balkisanji Agrawal Associate Professor Pathology,Pacific Medical College and Hospital,Udaipur Rajasthan
  • Suraj Jain
  • Sajjan S Surana
  • Sashi Sujanani
Keywords: TTIs, Voluntary Donors, Replacement Donors, Blood Bank, HIV, HBV, HCV, Syphilis, Malaria

Abstract

Background: Safe blood transfusion is of utmost importance as an unsafe blood transfusion bears lot of burden on human life and economy. Amongst the blood transfusion complications, transmission of certain infections like HIV, Hepatitis B, Hepatitis C and Syphilis are most significant for the long term detrimental side effects. The present study was carried out with an aim to assess the trend and seroprevalence of transfusion transmitted infections (TTIs)  among blood donors at our blood bank.Methods: The present retrospective study was carried out at blood bank attached to Pacific Medical College and Hospital, Udaipur, Rajasthan after ethical committee approval. Data regarding sex of the donor, type of donors and screening test results were collected from the records of blood bank over a period of 3 years (May 2014 - June 2016).Result: Total 2015 donors were registered of which 1944 (96.5%) were males and 71 (3.5%) were females. Replacement donors (68.7%) were more compared to voluntary donors (31.3%). Overall prevalence of TTIs in our blood bank is 2.38% of which prevalence of Syphilis (1.2%) was highest followed by HBV (0.89%), HIV (0.14%), and Malaria (0.1%).Conclusion: TTIs were more common in replacement donors than in voluntary donors, hence more voluntary donations need to be encouraged. Extensive donor screening by more sensitive methods to detect infections early can reduce the risk of TTIs. Despite high financial cost, adoption of newer screening methods like NAT can help in reducing the prevalence rate of TTIs to a large extent. DOI: 10.21276/APALM.1095

Author Biography

Preeti Balkisanji Agrawal, Associate Professor Pathology,Pacific Medical College and Hospital,Udaipur Rajasthan
Pathology

References

1. Sunderam S, Karir S, Haider S, Singh SB, Kiran A. Seroprevalence of Transfusion Transmitted infections among blood donors at Blood Bank of Rajendra Institute of Medical Sciences, Ranchi. Healthline Journal 2015; 6(1): 36-40.
2. Shaikh M, Bhople KS. Seroprevalence of Transfusion Transmitted infections in blood donors at a rural based tertiary care teaching hospital in India. IOSR Journal of Dental and Medical Sciences 2015; 14(10): 29-32.
3. Yadav BS, Varma AV, Singh P, Kumar R, Bandi PK. Seroprevalence of Transfusion-transmitted infections (TTIs) in blood donors: A study from Central India. Int J Med Sci Public Health 2016; 5(6): 1-5.
4. Arora D, Arora B, Khetarpal A. Seroprevalence of HIV, HBV, HCV and syphilis in blood donors in Southern Haryana. Indian J Pathol Microbiol 2010; 53: 308-309.
5. Pahuja S, Sharma M, Baitha B, Jain M. Prevalence and trends of markers of hepatitis C virus, hepatitis B virus and HIV in Delhi blood donors: A hospital based study. JP J Inf Dis 2007; 60: 389-91.
6. Singh B, Verma M, Kotru M, Verma K, Batra M. Prevalence of HIV and VDRL seropositivity in blood donors of Delhi. Indian J Med Res 2005; 122: 234-36.
7. Kakkar N, Kaur R, Dhanoa J. Voluntary donors need for a second look. Indian J Pathol Microbiol 2004; 47: 381-83.
8. Khageshan AP, Kulkarni KR, Baragundi MC. Seroprevalence of Co-infections among blood donors in a blood bank of a tertiary care health centre. APALM 2016; 3(1): A29-32.
9. Bhattacharya P, Chakraborty S, Basu SK. Significant increase in HBV, HCV, HIV and syphilis infections among blood donors in West Bengal Eastern India 2004-2005. Exploratory screening reveals high frequency of occult HBV infection. World J Gastroenterol 2007; 13: 3730-3733.
10. Shah N, Shah JM, Jhaveri P, Patel K, Shah CK, Shah NR. Seroprevalence of HBV, HCV, HIV and syphilis among blood donors at a tertiary care teaching hospital in Western India. Gujarat Medical Journal 2013; 68(2): 35-39.
11. Mandal R, Mondal K. Transfusion Transmissible infections among blood donors from a sub-Himalayan rural tertiary care centre in Darjeeling, India. Journal of Traditional and Complementary Medicine 2015; 1-6.
12. Philip J, Sarkar RS, Kumar S, Pathak A. Changing trends of Transfusion transmitted viral infections among blood donors in the last decade - A 10 year study in a large tertiary care blood bank (2000-2009). MJAFI 2015; 68(1): 28-32.
13. Pallavi P, Ganesh CK, Jayshree K, Manjunath GV. Seroprevalence and trends in Transfusion Transmitted Infections among blood donors in a university hospital blood bank – A 5 year study. Indian J Hematol Blood Transfus 2011 Mar; 27(1): 1-6.
14. Kaur H, Mannan R, Manjari M. Seroprevalence of the blood borne infections in blood donors: Our 11 year (2001-2011) experience in a tertiary care teaching hospital at Amritsar (Punjab). International Journal of Advanced Research 2014; 2(6): 967-71.
15. Fernandes H, D’Souza PF, D’Souza PM. Prevalence of Transfusion Transmitted Infections in voluntary and replacement Donors. Indian J Hematol Blood Transfus 2010; 26(3): 89-91.
Published
2017-04-05
Section
Original Article