Benign lymphoepithelial cyst in an adolescent female mimicking lymphoma: A diagnostic dilemma in a retrovirus negative patient

  • Somshankar Chowdhury MD Pathology Senior Resident, Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi-110029
  • Sufian Zaheer MD Pathology Associate Professor, Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi-110029
  • Preeti Sharma MD Pathology Senior Resident, Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi-110029
  • Ashish Kumar Mandal MD, PhD Pathology Director Professor, Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi-110029
Keywords: lymphoepithelial cyst, parotid, lymphoma, HIV

Abstract

Cystic lesions of the parotid gland are uncommon and may masqueradeneoplasms clinically. Benign lympho-epithelial cysts (BLEC) comprise the most common causes of the parotid gland swelling in human immunodeficiency virus (HIV)-positive patients. It is, however, less common amongst those not infected with HIV. We present a case of a12 years old female who presented with a swelling over left parotid region since one year.Local examination revealed a soft, cystic and non-tender swelling in the left parotid region measuring 5x4x3 cm. Serological investigations for viral markers were non-reactive.A differential diagnosis of granulomatous parotitis versus benign lymphoepithelial lesion was rendered on radiological investigations and superficial parotidectomy was planned. On histopathological examination, a cyst lined by cuboidal to low columnar lining was seen, underlying which, was dense lympho-plasmacytic infiltrate present in diffuse sheets. On immunohistochemistry, this lymphoid population was found to be reactive in nature (positive for kappa and lambda), thus excluding lymphoma. This case is being presented due to its rarity in HIV negative individuals and the histopathological diagnostic dilemma it presented with, mimicking a lymphoma. DOI: 10.21276/APALM.1163

Author Biographies

Somshankar Chowdhury, MD Pathology Senior Resident, Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi-110029
MD PathologySenior Resident, Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi-110029
Sufian Zaheer, MD Pathology Associate Professor, Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi-110029
MD PathologyAssociate Professor, Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi-110029
Preeti Sharma, MD Pathology Senior Resident, Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi-110029
MD PathologySenior Resident, Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi-110029
Ashish Kumar Mandal, MD, PhD Pathology Director Professor, Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi-110029
MD, PhD PathologyDirector Professor, Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi-110029

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Published
2017-08-25
Issue
Vol 4 No 4 (2017)
Section
Case Report

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