Breast Adenomyoepithelioma with predominance of morules: a cytological dilemma.
Keywords:
adenomyoepithelioma, breast, morules
Abstract
Adenomyoepithelioma is a rare, benign proliferative tumour that can involve the breast. It is usually present as a solitary, unilateral, painless mass at the periphery of the breast in women range in age from 26 to 82 years (average 63 years). Tumour sizes range from 0.5 to 8 cm. (average size 2.5 cm).We report a case of adenomyoepithelioma of right breast in a 58 years old female since two months with diagnostic difficulty on cytology, especially with morules predominance that merits documentation due to its rarity. On physical examination, it was a single well defined, lobulated, non mobile, firm mass of 10 x 8 x 5 cm in upper outer quadrant of right breast without associated axillary lymphadenopathy. Sonomammography showed well defined lobulated right breast mass with macrolobulations and cystic changes suggestive of phyllodes tumour. Wide local excision was performed and histopathological study revealed adenomyoepithelioma which is confirmed by P63 immunostain. DOI: 10.21276/APALM.1311References
1. Hamperl H et al.The myothelia (myoepithelial cells): normal state,regressive Changes, hyperplasia, tumors. Curr Top Pathol. 1970;53:161-220.
2. Khan L, Shrivastava S, Singh PK, Ather M. Benign breast myoepithelioma. Journal of Cytology. 2013; 30:62-64.
3. Rosen PP. Myoepithelial Neoplasms. Rosen’s Breast Pathology , 3rdedition. Lippincott Williams & Wilkins. New York. 2009;138-159.
4. Iyengar P, Ali S, Edi Brogi. Fine Niddle Aspiration Cytology of Mammary Adenomyopithelioma: A study of 12 patients. Cancer(Cancer Cytopathology). 2006;108:250-256.
5. SatyanarayanaV, Gole S.et al. Adenomyoepithelioma A Rare Breast Tumor: Case Studies with Review of the Literature. The Internet Journal of Pathology.2012;13:2.
6. Yoon JY, Chitale D. Adenomyoepithelioma of the breast: a brief diagnostic review. Arch Pathol Lab Med.2013 May;137(5):725-9.
7. Jian Zhu, Gaofeng Ni, Dan Wang, Qingqing He, Peifeng Li. Lobulated adenomyoepithelioma: A case report showing immunohistochemical profiles. Int J Clin Exp Pathol. 2015;8(11):15407-15411.
2. Khan L, Shrivastava S, Singh PK, Ather M. Benign breast myoepithelioma. Journal of Cytology. 2013; 30:62-64.
3. Rosen PP. Myoepithelial Neoplasms. Rosen’s Breast Pathology , 3rdedition. Lippincott Williams & Wilkins. New York. 2009;138-159.
4. Iyengar P, Ali S, Edi Brogi. Fine Niddle Aspiration Cytology of Mammary Adenomyopithelioma: A study of 12 patients. Cancer(Cancer Cytopathology). 2006;108:250-256.
5. SatyanarayanaV, Gole S.et al. Adenomyoepithelioma A Rare Breast Tumor: Case Studies with Review of the Literature. The Internet Journal of Pathology.2012;13:2.
6. Yoon JY, Chitale D. Adenomyoepithelioma of the breast: a brief diagnostic review. Arch Pathol Lab Med.2013 May;137(5):725-9.
7. Jian Zhu, Gaofeng Ni, Dan Wang, Qingqing He, Peifeng Li. Lobulated adenomyoepithelioma: A case report showing immunohistochemical profiles. Int J Clin Exp Pathol. 2015;8(11):15407-15411.
Published
2017-12-11
Issue
Section
Case Report
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access at http://opcit.eprints.org/oacitation-biblio.html).
