Histopathological spectrum of Nephrectomy specimen in a tertiary care centre: with an emphasis on Chronic Pyelonephritis
Keywords:
Nephrectomy, Renal cell carcinoma, Chronic Pyelonephritis
Abstract
Introduction:Nephrectomy is a common procedure in urological practice done for various conditions like calculi, chronic pyelonephritis, malignancy, obstruction, injury, etc with wide range of morbidity and mortality. In our country there is increased in number of end stage renal disease treated with dialysis and transplantation. So it is mandatory to study the spectrum of renal disease with special emphasis on Chronic pyelonephritis.Methods:This study was carried out in the Department of Pathology, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidhyapeeth University, Pondicherry. All the nephrectomy specimen received in the department over a period of three years (January, 2013 to December 2015) were included. A total of 34 cases of nephrectomy specimen were studied during this period.Results :Out of 34 cases of nephrectomy, 24 were done for inflammatory lesions, 8 cases for tumor and 2 cases shows cystic lesion. Out of 24 cases of pyelonephritis, 6 cases were associated with nephrolithiasis. Out of 8 tumor cases, 6 cases were Renal cell carcinoma.Conclusion:To conclude, Nephrectomies is mostly done for non-neoplastic lesion. CPN also seems to be associated with various findings like pyonephrosis, calculi, malignancies etc. Hence it is mandatory to study each CPN case in detail along with clinical and radiological findings. DOI:10.21276/APALM.1547References
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6.Divyashree B. Venkatesh NK, Madhusudhan HR, Hanumantha, Raju BK. Pathological spectrum of non-neoplastic diseases in the Nephrectomy specimens. J of Evidence Based Med & Hlthcare. 2014;1(15):1909-20.
7.Bashir N, Bashir Y, Shah P, et al. Histopathological study of renal tumors in resected Nephrectomy specimens - An experience from teritary care centre. National Journal of Medical Research. 2015;5(1):25-29.
8.Shaila, Nityananda BS, Arasi T. Spectrum of lesions in Nephrectomy specimens in tertiary care hospital. J of Evolution of Med and Dent Sci. 2015;4(73):12714-25.
9.Muhammad A, Khan K, Rana S. Nephrectomy- an overview, Pak J Surj,2012, 28(2):102-105.
10.Popat VC, Kumar MP, Udani D, Mundra MP, Vora DN, Porecha MM. A study on culprit factors ultimately demanding nephrectomy. Internet J Urol 2010;7.
11.Datta B, Moitra T, Chaudhury D N, Halder B. Analysis of 88 nephrectomies in a rural tertiary care centre of India. Saudi J Kid Dis Transpl. 2012;23(2):409-413.
12.El Malik EM, Memon SR, Ibrahim AL, Al Gizawi A, Ghali AM. Nephrectomy in Adults: Asir Hospital Experience. Saudi J Kidney Dis Transpl 1997;8:423-7.
13.Siddappa S, Ramprasad K, Muddegowda MK. Xanthogranulomatous pyelonephritis: A retrospective review of 16 cases. Korean J Urol. 2011;52:421-424.
14.Suryawanshi KH, Damle RP, Dravid NV, RawandaleAP, Surana A. Histomorphological Analysis of Lesions In Nephrectomy Specimens: A 4 Years Study In A Rural Hospital In India-Our Experience. Annals of Pathology and Laboratory Medicine, 2017; 4:3.
15.Han H, Segal AM, Seifter JL, Dwyer JT. Nutritional Management of Kidney Stones (Nephrolithiasis). ClinNutr Res 2015;4 :137-152 .
16.Saxena A, Sharma RK. Nutritional aspect of nephrolithiasis. Indian J Urol. 2010 Oct-Dec; 26(4): 523–530. FIGURE 1
2.Kumar MU, Yelikar BR, Patil G, Karigoudar MH, Pande P, Patil SB. Spectrum of histopathological lesions in Nephrectomy specimens- A two year study in a tertiary care hospital. International Journal of Research in Pharmaceutical and Biomedical Sciences. 2012; 3:1787-89.
3.Aiman A, Singh K, Yasir M. Histopathological spectrum of lesions in nephrectomy specimens: A five-year experience in a tertiary care hospital. J SciSoc 2013;40:148-54.
4.Murphy WM, Grignon DJ, Perlman EJ. Kidney tumours in adults. In: Silverberg SG, editor. Tumours of the Kidney, Bladder and Related Urinary Structures – AFIP Atlas of TumorPatholog. Series 4, chapt. 2. Washington DC; AFIP; 2004. p. 101-240.
5.Gairangbam S, Konjengbam R. Histopathological spectrum of non-neoplastic & neoplastic lesions in nephrectomy specimens. J. Evid. Based Med. Healthcare. 2016;3(16):627-29
6.Divyashree B. Venkatesh NK, Madhusudhan HR, Hanumantha, Raju BK. Pathological spectrum of non-neoplastic diseases in the Nephrectomy specimens. J of Evidence Based Med & Hlthcare. 2014;1(15):1909-20.
7.Bashir N, Bashir Y, Shah P, et al. Histopathological study of renal tumors in resected Nephrectomy specimens - An experience from teritary care centre. National Journal of Medical Research. 2015;5(1):25-29.
8.Shaila, Nityananda BS, Arasi T. Spectrum of lesions in Nephrectomy specimens in tertiary care hospital. J of Evolution of Med and Dent Sci. 2015;4(73):12714-25.
9.Muhammad A, Khan K, Rana S. Nephrectomy- an overview, Pak J Surj,2012, 28(2):102-105.
10.Popat VC, Kumar MP, Udani D, Mundra MP, Vora DN, Porecha MM. A study on culprit factors ultimately demanding nephrectomy. Internet J Urol 2010;7.
11.Datta B, Moitra T, Chaudhury D N, Halder B. Analysis of 88 nephrectomies in a rural tertiary care centre of India. Saudi J Kid Dis Transpl. 2012;23(2):409-413.
12.El Malik EM, Memon SR, Ibrahim AL, Al Gizawi A, Ghali AM. Nephrectomy in Adults: Asir Hospital Experience. Saudi J Kidney Dis Transpl 1997;8:423-7.
13.Siddappa S, Ramprasad K, Muddegowda MK. Xanthogranulomatous pyelonephritis: A retrospective review of 16 cases. Korean J Urol. 2011;52:421-424.
14.Suryawanshi KH, Damle RP, Dravid NV, RawandaleAP, Surana A. Histomorphological Analysis of Lesions In Nephrectomy Specimens: A 4 Years Study In A Rural Hospital In India-Our Experience. Annals of Pathology and Laboratory Medicine, 2017; 4:3.
15.Han H, Segal AM, Seifter JL, Dwyer JT. Nutritional Management of Kidney Stones (Nephrolithiasis). ClinNutr Res 2015;4 :137-152 .
16.Saxena A, Sharma RK. Nutritional aspect of nephrolithiasis. Indian J Urol. 2010 Oct-Dec; 26(4): 523–530. FIGURE 1
Published
2017-10-30
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