Efficacy of Pulse Co-oximeter in Hemoglobin Estimation: A non invasive method
Keywords:
Pulse Co-oximeter, Non invasive method, Bland Altmann Analysis
Abstract
Background: Total Hemoglobin(Hb) measurement is one of the most common and important parameter that is investigated in the laboratory.This non invasive method allows pain free continuous online patient monitoring with minimum risk of infection and facilitates real time data monitoring allowing immediate clinical reaction to the measured data. The objective of the study is to test the efficacy of pulse co-oximeter .Methods: Present study is a prospective descriptive study. A total of 261 patients enrolled for the study after their consent. Non invasively measured SpHb values and invasively measured Hb values were then compared by using Bland Altman statistical analysis . Result: Pulse co-oximeter recorded/displayed SpHb in 90.8% patients and did not display SpHb in 9.2% of patients. Out of which 73-75% patients Hb showed variation of less than or equal to 2gms and 20-24% patients Hb showed variation of more than 2 gms. On Bland Altmann comparative analysis of SpHb and Hb revealed bias and limits of agreement was 0.2+3.3gm/d and 95% of the measurements fell within two standard deviation of the mean difference and P value < 0.001 represents good correlation between SpHb and Hb of Lab1 and Lab 2.Conclusion: Pulse co-oximeter can be used as a screening tool for Hb measurement at out patient departments, blood camps, casuality, ICU and labor rooms. It determines Hb instantly and non invasively. Further studies are needed to determine financial aspects and needs upgradation in terms of accuracy of the instrumentDOI:10.21276/APALM.1558References
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8. Macknet MR, Allard M, Applegate R. The accuracy of noninvasive and continuous total hemoglobin measurement by pulse CO-Oximetry in human subjects undergoing hemodilution. Anesth Analg.2010; 111:1424–26.
9.Frasca D, Dahyot-Fizelier C, Catherine K. Accuracy of a continuous noninvasive hemoglobin monitor in intensive care unit patients. Crit Care Med.2011; 39:2277–82.
10.Causey MW, Miller S, Foster A et al: Validation of noninvasive hemoglobin measurements using the Masimo Radical-7 SpHb Station. Am J Sur.j 2011; 201:592–98.
11.Goldman JM, Petterson MT, Kopotic RJ, Barker SJ. Masimo signal extraction pulse oximetry. J Clin Monit Comput. 2000;16:475–83.
12.Ma'ayan L and Choppe L. Non-Invasive Hemoglobin Screening for Diagnosis and Monitoring of Anemia. fnwein@gmail.com.
13.Hadar E, Raban O, Bouganim T, Tenenbaum K, Hod M. Precision and accuracy of noninvasive hemoglobin measurement during pregnancy. The Journal of Maternal-Fetal and Neonatal Medicine,2012;25(12):2503-06.
14. Vora H, Desai P. Invasive versus noninvasive hemoglobin measurement by pulse CO-Oximeter in neonates admitted to NICU. NHL Journal of Medical Sciences.2014;3(1):68-71.
15. Nicholas C, George R.Validation of non invasive haemoglobin measurement by pulse CO-Oximeter in newborn infants with birth weight less than 3000 gms: pediatric academi societies annual meeting 2013,may 2013.
16.Van Woerkom R, El-Rify ES, Cerussi A, et al. Non-invasive diffuse optical Spectroscopy measures tissue response to red blood cell transfusion in low birth weight infants. Pediatr Res.2003;353 :361
17. Gayat E, Bodin A, Sportiello C, Boisson M, Dreyfus JF, Mathieu E et al. Performance evaluation of a noninvasive hemoglobin monitoring device. Ann Emerg Med. 2011;57:330–3.
18. Miller RD, Ward TA, Shiboski SC, Cohen NH. A comparison of three methods of hemoglobin monitoring in patients undergoing spine surgery. Anesth Analg. 2011;112:858-63.
19. Ruckman JS. A comparative study of total hemoglobin measurement technology: noninvasive pulse cooximetry and conventional methods. Master thesis,University of Connecticut 2011.
2.Zwart A, van Assendelft OW, Bull BS. Recommendations for reference method for haemoglobinometry in human blood (ICSH standard 1995) and specifications for international haemiglobinocyanide standard (4th edition). JClin Pathol.1996; 49:271–4.
3.Allard MR, Macknet M, Kherzi S et al: Accuracy of noninvasive hemoglobin measurements by Pulse CO-Oximetry in hemodilution subjects.2009;4:184.
4.Rajashree D, Anagha P. Non-Invasive Optical Sensor for Hemoglobin Determination. IJERA. 2013;3(2):559-62.
5. Bland JM, Altman DG: Agreement between methods of measurement with multiple observations per individual. J BiopharmStat. 2007; 17:571–82.
6.Paul BB, Dena MR. Maximizing the laboratory setting for testing devices and understanding statistical output in pulse oximetry. Anesth Analog.2007; 105:85–94.
7.Frasca D, Dahyot-Fizelier C, Catherine K. Accuracy of a continuous noninvasive hemoglobin monitor in intensive care unit patients. Crit CareMed.2011; 39:2277–82.
8. Macknet MR, Allard M, Applegate R. The accuracy of noninvasive and continuous total hemoglobin measurement by pulse CO-Oximetry in human subjects undergoing hemodilution. Anesth Analg.2010; 111:1424–26.
9.Frasca D, Dahyot-Fizelier C, Catherine K. Accuracy of a continuous noninvasive hemoglobin monitor in intensive care unit patients. Crit Care Med.2011; 39:2277–82.
10.Causey MW, Miller S, Foster A et al: Validation of noninvasive hemoglobin measurements using the Masimo Radical-7 SpHb Station. Am J Sur.j 2011; 201:592–98.
11.Goldman JM, Petterson MT, Kopotic RJ, Barker SJ. Masimo signal extraction pulse oximetry. J Clin Monit Comput. 2000;16:475–83.
12.Ma'ayan L and Choppe L. Non-Invasive Hemoglobin Screening for Diagnosis and Monitoring of Anemia. fnwein@gmail.com.
13.Hadar E, Raban O, Bouganim T, Tenenbaum K, Hod M. Precision and accuracy of noninvasive hemoglobin measurement during pregnancy. The Journal of Maternal-Fetal and Neonatal Medicine,2012;25(12):2503-06.
14. Vora H, Desai P. Invasive versus noninvasive hemoglobin measurement by pulse CO-Oximeter in neonates admitted to NICU. NHL Journal of Medical Sciences.2014;3(1):68-71.
15. Nicholas C, George R.Validation of non invasive haemoglobin measurement by pulse CO-Oximeter in newborn infants with birth weight less than 3000 gms: pediatric academi societies annual meeting 2013,may 2013.
16.Van Woerkom R, El-Rify ES, Cerussi A, et al. Non-invasive diffuse optical Spectroscopy measures tissue response to red blood cell transfusion in low birth weight infants. Pediatr Res.2003;353 :361
17. Gayat E, Bodin A, Sportiello C, Boisson M, Dreyfus JF, Mathieu E et al. Performance evaluation of a noninvasive hemoglobin monitoring device. Ann Emerg Med. 2011;57:330–3.
18. Miller RD, Ward TA, Shiboski SC, Cohen NH. A comparison of three methods of hemoglobin monitoring in patients undergoing spine surgery. Anesth Analg. 2011;112:858-63.
19. Ruckman JS. A comparative study of total hemoglobin measurement technology: noninvasive pulse cooximetry and conventional methods. Master thesis,University of Connecticut 2011.
Published
2017-10-30
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