Leiomyosarcoma Of Rectum Mimicking Primary Ovarian Tumour
Keywords:
Ovarian tumor, leiomyosarcoma, rectum, histopathology, immunohistochemistry
Abstract
Leiomyosarcoma of rectum is a very rare mesenchymal tumour with an incidence of approximately 0.1% of all colorectal malignancies. Because of its rarity, its diagnosis, treatment and pathology often present challenges to the clinicians. The characteristics of this tumour, such as its anatomical location, heterogenous solid features on imaging and non specific lower gastrointestinal tract symptoms can be confused with those of a primary ovarian tumour. Further, a synchronously growing primary ovarian tumour may add more confusion to the diagnosis. We have reported this case of rectal leiomyosarcoma with synchronously occuring primary ovarian tumour in an elderly female presenting with a large lower abdominal mass;where clinical and radiological findings are more suggestive of a primary malignant ovarian tumour with rectal metastasis. In such situation the possibility of other primary tumor of GIT specifically leiomyosarcoma should be looked for.Here Postoperative histopathological examination and immunohistochemistry gives confirmatory diagnosis.DOI:10.21276/APALM.1561References
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2. Kahlifa AA,Bong WL,Rao VK,Williams MJ:Leiomyosarcoma of the rectum.Report of a case and review of the literature.Dis Colon Rectum 1986,29:427-432
3. Yung-Tae Ouh,Jin Hwa Hong, Kyung- Jin Min, Kyeong- A So and Jae Kwan Lee. Leiomyosarcoma of the rectum mimicking primary ovarian carcinoma: a case report .Journal of Ovarian Research 2013, 6:27 http://www.ovarianresearch.com/content/6/1/27
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5. N. Sahil et al : Unusual evolution of leiomyosarcoma of the rectum: a case report and review of the literature.Journal of Medical case Report 2016,10:249
6. Evans HL . Smooth muscle tumor of the gastrointestinal tract. A study of 56 cases followed for a minimum of 10 years . Cancer 1985:56:2242-50.
7. Randleman CD Jr, Wolff BG, Dozois RR, et al. Leiomyosarcoma of the Rectum and anus. A series of 22 cases. Int J Colorectal Dis 1989;4:91-6.
8. Walsh TH, Mann CV. Soomth muscle neoplasm of the rectum and anal canal. Br J Surgery 1984;71:597-9.
9. Friesen R, Moyana TN, Murray RB, et al. Colorectal leiomyosarcoma: a Patholobiologic study with long term follow-up. Can J Surg 1992:35:505-8.
10. Lee SH,Ha HK,Byun JY,Kim AY,Cho KS, Lee YR,Park HW,Kim PN,Lee MG,Auh YH:Radiological features of leiomyomatous tumours of the colon and rectum.J Comput Assist Tomogr 2000,24:407-412.
11. Chiara O, Canini T, Segala M, Tiberio GA, Gulini SM, Tiberio G. Smooth muscle - cell tumor of the gastroenteric tract. A review of cases. Minerva Chir. 1997;52(10):1147-55.
12. Weiss SW, Goldblum JR . Enzinger and Weiss’s soft tissue tumors. 5th ed. St Louis:Mosby; 2008.p 546-55.
13. Rbin YM, Pnel N, Perot G, et al. Transgelin is a noval marker of smooth muscle differentiation that improves diagnostic accuracy of leiomyosarcoma: a comparative immunohistochemical reappraisal of myogenic marker in900 soft tissue tumors. Mod Pathol. 2013;26(4):502-10.
14. Nemer FD, Stoeckinger JM, Evan OT. Smooth muscle rectal tumors: A therapeutic dilemma.Dis Colon Rectum.1977;20:405-13.
15. Christopher D.M. Fletcher. Diagnostic Histopathology of tumours Fourth edition Elsevier Philadelphia. 2013
16. Eitan N, Auslander L, Cohen Y. Leiomyosarcoma of the rectum : report of three cases. Dis Colon, Rectum 1978;21:444-6.
2. Kahlifa AA,Bong WL,Rao VK,Williams MJ:Leiomyosarcoma of the rectum.Report of a case and review of the literature.Dis Colon Rectum 1986,29:427-432
3. Yung-Tae Ouh,Jin Hwa Hong, Kyung- Jin Min, Kyeong- A So and Jae Kwan Lee. Leiomyosarcoma of the rectum mimicking primary ovarian carcinoma: a case report .Journal of Ovarian Research 2013, 6:27 http://www.ovarianresearch.com/content/6/1/27
4. Talikoti MA, Deo SS,Shukla NK,Kallianpur AA,Gupta M:A rare case of giant leiomyosarcoma in a filarial scrotum:A case report.World J Surg Oncol 2011,9:20.
5. N. Sahil et al : Unusual evolution of leiomyosarcoma of the rectum: a case report and review of the literature.Journal of Medical case Report 2016,10:249
6. Evans HL . Smooth muscle tumor of the gastrointestinal tract. A study of 56 cases followed for a minimum of 10 years . Cancer 1985:56:2242-50.
7. Randleman CD Jr, Wolff BG, Dozois RR, et al. Leiomyosarcoma of the Rectum and anus. A series of 22 cases. Int J Colorectal Dis 1989;4:91-6.
8. Walsh TH, Mann CV. Soomth muscle neoplasm of the rectum and anal canal. Br J Surgery 1984;71:597-9.
9. Friesen R, Moyana TN, Murray RB, et al. Colorectal leiomyosarcoma: a Patholobiologic study with long term follow-up. Can J Surg 1992:35:505-8.
10. Lee SH,Ha HK,Byun JY,Kim AY,Cho KS, Lee YR,Park HW,Kim PN,Lee MG,Auh YH:Radiological features of leiomyomatous tumours of the colon and rectum.J Comput Assist Tomogr 2000,24:407-412.
11. Chiara O, Canini T, Segala M, Tiberio GA, Gulini SM, Tiberio G. Smooth muscle - cell tumor of the gastroenteric tract. A review of cases. Minerva Chir. 1997;52(10):1147-55.
12. Weiss SW, Goldblum JR . Enzinger and Weiss’s soft tissue tumors. 5th ed. St Louis:Mosby; 2008.p 546-55.
13. Rbin YM, Pnel N, Perot G, et al. Transgelin is a noval marker of smooth muscle differentiation that improves diagnostic accuracy of leiomyosarcoma: a comparative immunohistochemical reappraisal of myogenic marker in900 soft tissue tumors. Mod Pathol. 2013;26(4):502-10.
14. Nemer FD, Stoeckinger JM, Evan OT. Smooth muscle rectal tumors: A therapeutic dilemma.Dis Colon Rectum.1977;20:405-13.
15. Christopher D.M. Fletcher. Diagnostic Histopathology of tumours Fourth edition Elsevier Philadelphia. 2013
16. Eitan N, Auslander L, Cohen Y. Leiomyosarcoma of the rectum : report of three cases. Dis Colon, Rectum 1978;21:444-6.
Published
2018-02-27
Issue
Section
Case Report
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