Steroid cell tumour- NOS of the ovary in a young female
Keywords:
Virilizing, steroid cell, young
Abstract
Sex cord stromal cell tumours constitute 5-8 % of all ovarian neoplasms. Steroid cell tumours are a type of sex cord stromal cell tumours. The name “Steroid cell” stands for the morphology and the functionality of these tumours. Steroid cell tumours- Not otherwise specified constitute about 56% of all steroid cell tumours and presents more commonly with androgenic manifestations in third to fourth decade. We present a case, 22 year old, who presented with virilizing symptoms. MRI was suggestive of an right ovarian mass for which right salpingo-oophorectomy was done. Histopathology revealed features classical of Steroid cell tumour- Not otherwise specified. We present the case for a relatively younger age at presentation and the classical histomorphology.DOI:10.21276/APALM.1597References
1. Baloglu A, Bezircioglu I, Cetinkaya B, Karci L, Bicer M. Development of secondary ovarian lesions after hysterectomy without oophorectomy versus unilateral oophorectomy for benign conditions: a retrospective analysis of patients during a nine-year period of observation. Clin Exp Obstet Gynecol. 2010;37:299-302
2. Outwater EK, Wagner BJ, Mannion C, McLarney JK, Kim B. Sex cord-stromal and steroid cell tumours of the ovary. Radiographics. 1998;18(6):1523-46.
3. Cserepes E, Szucs N, Patkos P, Csapo Z, Molnar F, Toth M, et al. Ovarian steroid cell tumour and a contralateral ovarian thecoma in a postmenopausal woman with severe hyperandrogenism. Gynecol. Endocrinol. 2002;16(3):213-16
4. Hayes MC, Scully RE. Ovarian steroid cell tumours (not otherwise specified): A clinic-pathological analysis of 63 cases. Am J Surg Pathol. 1987;11(11):835–45.
5. Tumours of the Breast and the Female Genital system. WHO Classification of Tumours. 2003. 160-163
6. Paraskevas M, Scully RE. Hiluscell tumour of the ovary. A clinico-pathological analysis of 12 Reinke crystal-positive and nine crystal- negative cases. Int J Gynecol Pathol. 1989;8(4):299–310.
7. Scully RE. Stromal luteoma of the ovary. A distinctive type of lipoid-cell tumour. Cancer. 1964;17:769–78.
8. Ghazala Mehdi, Hena A. Ansari, Rana K. Sherwani, Khaliqur Rahman, and Nishat Akhtar, Ovarian Steroid Cell Tumour: Correlation of Histopathology with Clinicopathologic Features. Pathology Research International. 2011.
9. Jiang W, Tao X, Fang F, Zhang S, Xu C. Benign and malignant ovarian steroid cell tumours, not otherwise specified: case studies, comparison, and review of the literature. J Ovarian Res. 2013;6:53.
10. Swain J, Sharma S, Prakash V, Agrawal NK, Singh SK. Steroid cell tumour: a rare cause of hirsutism in a female. Endocrinology, diabetes and metabolism case reports. 2013.
2. Outwater EK, Wagner BJ, Mannion C, McLarney JK, Kim B. Sex cord-stromal and steroid cell tumours of the ovary. Radiographics. 1998;18(6):1523-46.
3. Cserepes E, Szucs N, Patkos P, Csapo Z, Molnar F, Toth M, et al. Ovarian steroid cell tumour and a contralateral ovarian thecoma in a postmenopausal woman with severe hyperandrogenism. Gynecol. Endocrinol. 2002;16(3):213-16
4. Hayes MC, Scully RE. Ovarian steroid cell tumours (not otherwise specified): A clinic-pathological analysis of 63 cases. Am J Surg Pathol. 1987;11(11):835–45.
5. Tumours of the Breast and the Female Genital system. WHO Classification of Tumours. 2003. 160-163
6. Paraskevas M, Scully RE. Hiluscell tumour of the ovary. A clinico-pathological analysis of 12 Reinke crystal-positive and nine crystal- negative cases. Int J Gynecol Pathol. 1989;8(4):299–310.
7. Scully RE. Stromal luteoma of the ovary. A distinctive type of lipoid-cell tumour. Cancer. 1964;17:769–78.
8. Ghazala Mehdi, Hena A. Ansari, Rana K. Sherwani, Khaliqur Rahman, and Nishat Akhtar, Ovarian Steroid Cell Tumour: Correlation of Histopathology with Clinicopathologic Features. Pathology Research International. 2011.
9. Jiang W, Tao X, Fang F, Zhang S, Xu C. Benign and malignant ovarian steroid cell tumours, not otherwise specified: case studies, comparison, and review of the literature. J Ovarian Res. 2013;6:53.
10. Swain J, Sharma S, Prakash V, Agrawal NK, Singh SK. Steroid cell tumour: a rare cause of hirsutism in a female. Endocrinology, diabetes and metabolism case reports. 2013.
Published
2018-02-27
Issue
Section
Case Report
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access at http://opcit.eprints.org/oacitation-biblio.html).
