Fine needle aspiration cytology of solitary thyroid nodule with histopathology correlation

  • MS Susmitha
  • Veena S Department Of Pathology, Shimoga Institute Of Medical Science. Sagar Road. Shimoga
  • Ramesh K Babu
Keywords: Thyroid, nodule, solitary, cytology

Abstract

Background: Solitary thyroid nodule (STN) is a localized thyroid enlargement with apparently normal rest of the gland clinically. Preoperative Fine Needle Aspiration Cytology (FNAC) aids in distinguishing benign and malignant nodules and planning the treatment. Based on the cytology findings, patients can be followed in cases of benign diagnosis and thereby decreasing the rate of unnecessary surgery. However the accuracy of FNAC is found to be varied in different studies. The aim of the study was to study the cytological findings in STN and to correlate the FNAC and histopathology results.Methods:A retrospective study including FNAC of 107 patients presenting with solitary thyroid nodule from January 2015 to June 2017 was done at Department of Pathology. Cytology and histopathology correlation was available in 40 cases.   Results: Solitary thyroid nodules involved females more commonly than males with a ratio of 10.8:1. Malignancy was present in 12.5% of cases and papillary carcinoma was the commonest malignancy. For malignancies, FNAC showed sensitivity of 40%, specificity of 97.1%, Positive predictive value of 66.6%, Negative predictive value 91.9% and Efficacy of 90%.Conclusion:FNAC of solitary thyroid nodules has high specificity and efficacy. Low sensitivity of FNAC in STN necessitates caution and patient follow up in cases with cytological benign diagnosis. DOI: 10.21276/APALM.1620

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Published
2017-12-22
Issue
Vol 4 No 6 (2017)
Section
Original Article

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