Clinico Histopathological Correlation Study of Leprosy

  • Bharat Ankush Ghodke Department Of Pathology, Grant Government Medical College and Sir JJ group of Hospitals, Mumbai
  • Arvind G Valand Department Of Pathology, Grant Government Medical College and Sir JJ group of Hospitals, Mumbai(India)
  • Aradhana Bhubaneswar Deka Department Of Pathology, Grant Government Medical College and Sir JJ group of Hospitals, Mumbai(India)
  • Sushma Nagsen Ramraje Department Of Pathology, Grant Government Medical College and Sir JJ group of Hospitals, Mumbai(India)
  • Zeba Shamshad Ali Department Of Pathology, Grant Government Medical College and Sir JJ group of Hospitals, Mumbai(India)
Keywords: Tuberculoid, histopathology, leprosy, granuloma

Abstract

Background: Aim of the study was to study the histomorphological changes in leprosy, the clinicopathological correlation of different types of leprosy lesions and cases of clinically diagnosed lepra reaction.Methods: One hundred and twelve patients of clinically diagnosed leprosy were chosen. Skin biopsy was performed, fixed in 10% buffered formalin, processed, sectioned and stained with Hematoxylin and Eosin as well as Modified Fite Faraco stain.Result: Of the one hundred and twelve patients enrolled in the study (age range from 7 to 70 years) 90 patients were males and 22 were females. All cases were classified according to the Ridley Jopling Scale. Correlation between clinical diagnosis and histopathological type of leprosy and lepra reactions was done.Conclusion: Leprosy is more common in males than in females having a ratio of 4:1.The commonest histopathological subgroup was tuberculoid leprosy.DOI: 10.21276/APALM.1645

Author Biography

Bharat Ankush Ghodke, Department Of Pathology, Grant Government Medical College and Sir JJ group of Hospitals, Mumbai
Blood Transfuion Officer (MD Pathology)Department of Pathology Sir JJ Group of Hospitals and GGMC, Mumbai

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Published
2017-12-22
Issue
Vol 4 No 6 (2017)
Section
Original Article

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