Basosquamous Carcinoma Of Nose: A Rare Tumor Diagnosed On Cytology

  • Manupriya Sharma (Pathology), Dr RP Govt. Medical College, Kangra at Tanda (HP) India
  • Suman Singh (Pathology), Dr RP Govt. Medical College, Kangra at Tanda (HP) India
  • Rashmi Kaul (Pathology), Dr RP Govt. Medical College, Kangra at Tanda (HP) India
  • V K Mahajan (Dermatology), Dr RP Govt. Medical College, Kangra at Tanda (HP) India
Keywords: Basosquamous carcinoma, nose, cytology, diagnosis


Basosquamous carcinoma (BSC) is a rare subtype of basal cell carcinoma (BCC) with an incidence of 1-2%. BSC is characterized by aggressive nature in terms of poor prognosis and distant metastasis. Unlike BCC which is a rodent ulcer with local invasion and no distant metastasis. BSC is usually diagnosed on histopathology examination after biopsy. We hereby present a case report of diagnosis of BSC on cytological examination followed by confirmation with histopathology. To the best of our knowledge, there is the first case reported in literature on this matter. We emphasize the importance of thorough cytological examination so as to suspect and finally confirm this rare entity.DOI: 10.21276/APALM.1679

Author Biography

Manupriya Sharma, (Pathology), Dr RP Govt. Medical College, Kangra at Tanda (HP) India
Dr Manupriya Sharma, MD, DNB,                       Assistant Professor, (Pathology)                            Dr RPGMC Kangra at Tanda (HP).Set No. 112, Vivekanand Hostel, Dr RPGMC,                Kangra HP, INDIA: 176001Phone No. 91-8628000105Email:


1. Wermker K, Roknic N, Goessling K, Klein M, Schulze HJ, Hallermann C. Basosquamous carcinoma of the head and neck: clinical and histologic characteristics and their impact on disease progression. Neoplasia. 2015 Mar;17(3):301-5

2. De Stefano A, Dispenza F, Petrucci AG, Citraro L, Croce A. Features of biopsy in diagnosis of metatypical basal cell carcinoma (Basosquamous Carcinoma) of head and neck. Otolaryngol Pol. 2012 Nov-Dec;66(6):419-23

3. Garcia C, Poletti E, Crowson AN. Basosquamous carcinoma. J Am Acad Dermatol.2009 Jan;60(1):137-43

4. Linton OR, Moore MG, Brigance JS, Gordon CA, Summerlin DJ, McDonald MW. Prognostic significance of basaloid squamous cell carcinoma in head and neck cancer. JAMA Otolaryngol Head Neck Surg. 2013 Dec;139(12):1306-11

5. Fritsch VA, Gerry DR, Lentsch EJ. Basaloid squamous cell carcinoma of the oral cavity: an analysis of 92 cases. Laryngoscope. 2014 Jul;124(7):1573-8

6. Verkouteren JAC, Ramdas KHR, Wakkee M, Nijsten T. Epidemiology of basal cell carcinoma: scholarly review. Br J Dermatol. 2017 Aug;177(2):359-372

7. Dessinioti C, Antoniou C, Katsambas A, Stratigos AJ. Basal cell carcinoma:what's new under the sun. Photochem Photobiol. 2010 May-Jun;86(3):481-91
Case Report