Lung abscess due to candida tropicalis in a HIV positive immunocompromised patient: a rare case report from central India.
Keywords:
Lung abscess, Non-albicans candida, Candida tropicalis, Human immunodeficiencyVirus, Immunocompromised host
Abstract
Invasive candidiasis is an emerging fungal infection in immunocompromised patients globally. Presentation of candidiasis in Human immunodeficiency virus (HIV) infected patients as lung abscess is very rare in tropical country like India. Here we report a case of lung abscess due to Candida tropicalis in a HIV positive immunocompromised patient. After diagnosis of C. tropicalis as pathogen the patient was treated by Amphotericin B and Fluconazole, the lung abscess got resolved but the patient succumbed to his illness may be due to nephrotoxicity of Amphotericin B and poor physical condition due other AIDS related comorbidities. The purpose of this article is to take note of this emerging fungal infection in India and also to review literature in this case.DOI:10.21276/APALM.1739References
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2. Takayanagi N, Kagiyama N, Ishiguro T, Tokunaga D, Sugita Y. Etiology and outcome of community-acquired lung abscess. Respiration2010; 80(2):98-105.
3. Goel N, Ranjan P, Aggarwal R, ChaudharyJ, Nanda S. Emergence of Non-albicans candida in neonatal septicaemia and antifugal susceptibility: Experience from a tertiary care center. Journal of Laboratory Physicians. 2009; 1(2):53-55.
4. Gupta A, Bhowmik D, Dogra P, Mendonca S, Gupta A. Candia lung abscess in renal transplant recipient. Saudi J Kidney Dis Transpl .2013;24(2): 315-7.
5. Yazbeck MF, Dahdel M, Kalra A, et al. Lung abscess: update on microbiology and management. Am J Ther 2014;21:217-21.
6. Nissapatorn V, Lee C, Fatt QK, Abdullah KA. AIDS-related opportunistic infections in Hospital Kuala Lumpur. Jpn J Infect Dis. 2003; 56: 187-92.
7. Ando K, Okhuni Y, Matsunuma R, et al. Prognostic lung abscess factors. Kansenshogaku Zasshi 2010;84:425-30.
8. Dixon TC, Steinbach WJ, Benjamin DK, Williams LW, Myers LA.. Disseminated Candida tropicalis in a patient with chronic mucocutaneous candidiasis. South Med J. 2004;97: 788–790.
9. Fleck R, Dietz A, Hof H. In vitro susceptibility of Candida species to five antifungal agents in a German university hospital assessed by the reference broth microdilution method and Etest. J Antimicrob Chemother 2007; 59: 767-71.
10. Gilbert D. Amphotericin B nephrotoxicity. Journal of Antimicrobial chemotherapy. 2002; 49:37-41.
11. Rubin AE and Alroy GG. Candida albicans abscess of lung. Thorax. 1977 1977; 32:373-376.
12. Gupta P, Agarwal D, Yadav R. lung abscess due to pulmonary candidiasis. Lung India .2006; 23: 160-162.
Published
2018-03-22
Issue
Section
Case Report
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