A rare renal neoplasm with dimorphic histology and mucinous stroma
Mucinous tubular and spindle cell carcinoma (MTSCC) is a rare and recently described histologic variant of renal cell carcinoma (RCC). Usually considered as a tumor of low malignant potential it is important to appreciate the characteristic histologic features to arrive at the correct diagnosis. We report a case of MTSCC in a female aged 54years who presented with a long standing vague loin pain. Diagnostic work-up showed a renal mass suggestive of RCC. With the preoperative diagnosis of RCC followed by nephrectomy showed a completely different histology of a rare tumour with tubules, spindle cells and mucinous stroma consistent with MTSCC, a low grade tumour with good prognosis.
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Lima MS, Barrous-Silva GE, Pereira RA, Ravinal RC, Junior ST, Costa RS and Mugila VF. The imaging and pathological features of a mucinous tubular and spindle cell carcinoma of the kidney: a case report. World J of Surgical Oncology. 2013;11:34
Paner GP, Srigley JR, Radhakrishnan A, Cohen C, Skinnider BF, Tickoo SK et al. Immunohistochemical analysis of mucinous tubular and spindle cell carcinoma and papillary renal cell carcinoma of the kidney: significant immunophenotypic overlap warrants diagnostic caution. Am J Surg Pathology. 2006;30:13-9
Sun N, Fu Y, Wang Y, Tian T, An W, Yuan T. Mucinous tubular and spindle cell carcinoma of the kidney: A case report and review of the literature. Oncology letters-spandidos publications. DOI: 10.3892/ol.2014.1783
Higgins JP and Rouse RP. Mucinous tubular and spindle cell carcinoma of the kidney. Stanford school of medicine. Jan 2011 http://surgpathcriteria.stanford.edu/kidney/mucinous-tubular-spindle-cell-carcinoma/
Williamson S. Mucinous and spindle cell carcinoma. July 2012. www.pathologyoutlines.com/topic/kidneytumormalignantmucinoustubular.html
Wu X, Chen Y, Sha J, Zhao L, Huang J, Bo J et al. Renal mucinous tubular and spindle cell carcinoma: a report of 8 cases and review of the literature. Diagnostic pathology. 2013;8:206
Jung SJ, Yoon HK, Chung J, Ayala GA, Ro JY. Mucinous tubular and spindle cell carcinoma of the kidney with neuroendocrine differentiation. Am J of clinical pathology. 2006;125:99-104
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