Cytomorphology of Primary Adenoid Cystic Carcinoma Of Lung: An Exceedingly Rare Case
Keywords:
Adenoid Cystic Carcinomas, Pulmonary Tumor, Cytology, Hyaline Globules,
Abstract
Primary adenoid cystic carcinoma (ACC) of lung is a rare tumor, and probably accounts for 0.04-0.2% of all primary pulmonary tumors. It was formerly referred to as bronchial adenoma implying a benign glandular neoplasm. However, it is now considered to be a low-grade bronchial carcinoma. Pulmonary ACC usually arise in the proximal tracheobronchial tree, and are regarded as a slowly growing tumor.A 20 year female was admitted with complain of cough without expectoration, weight loss, fever and anorexia since 20 days. In Ultrasound Sonography (USG) approx. 10x7 cm in size of well defined mixed echogenic lesion was noted at left upper zone. USG guided Fine Needle Aspiration Cytology was done. Cytopathology was suggesting of primary adenoid cystic carcinoma of lung. Fine needle aspiration cytology is simple method and useful in pre-operative diagnosis. However, diagnosis of adenoid cystic carcinoma of lung is difficult by cytologically. So, it is confirmed by histolopathological study.References
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2) Travis WD, Travis LB, Devesa SS. Lung cancer. Cancer 1995;75:191-202
3) Travis WD, Brambilla E, Muller-hermelink HK, Harris CC. Pathology and genetics of lung, Pleura, thymus, and heart. Lyon: IARC press;2004,p65-6
4) Spencer H. Pathology of the lung. 4 th ed. Oxford: Pergamon; 1985. p. 968-9
5) Reid JD. Adenoid cystic carcinoma (cylindroma) of the bronchial tree. Cancer 1952;5:6894
6) S.Mukherjee. A Rare Case of Primary Adenoid Cystic Carcinoma of Lung, Kolkata, India 2014:56:175-177.
7) Dixit R, Nuval P. Pulmonary adenoid cystic carcinoma: an unusual presentation. Lung India 2007;24:28-9.
8) Sterrett G, Frost F, Whitaker D. Tumors of lung and mediastinum. In: Gray W, McKee GT, editors. Diagnostic cytopathology. 2nd ed. London: Churchill Livingstone; 2003. p. 97-131.
9) Mondal A, Saha DK. Primary adenoid cystic carcinoma of the lung: a clinicopathologic study. Indian J Thorac Cardiovascular Surg 2008; 24:240-3.
10) Holst VA, Marshall CE, Moskaluk CA, Frierson HF Jr. KIT protein expression and analysis ofc-kit gene mutation in adenoid cystic carcinoma. Mod Pathol 1999; 12:956-60
11) Kawashima O, Hirai T, Kamyoshihara M, Ishikawa S, Morishata Y. Primary adenoid cystic carcinoma in the lung:report of two cases and therapeutic consideration. Lung Cancer 1998; 19:211-7
12) Bhattacharyya T, Bahl A, Kapoor R, Bal A, Das A, Sharma SC. Primary adenoid cystic carcinoma of lung: a case report and review of the literature. J Can Res Ther 2013; 9:302-4.
Published
2015-11-01
Issue
Section
Case Report
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