CD4 cell count analysis among HIV patients at a tertiary hospital in South India

  • Vanisri HR Chamarajanagar Institute of Medical sciences
  • Vadiraja N
Keywords: CD4 count, HIV, Anti-retroviral therapy


Background: HIV (Human Immunodeficiency Virus) infection is characterized by a gradual deterioration of immune function. CD4 cell counts generally decrease as HIV progresses in untreated HIV-infected subjects .The present study was undertaken to know the effect of ART (Anti retroviral therapy) and the status of CD4 counts in study patients and among the genders in HIV patients.Methods: This was a cross sectional study on secondary data maintained in the ART centre for the period of 6 months from March 2015 to October 2015. The patient reports (150 cases) in the ART centre during the period of the study (6 months) were selected. CD4 cell count was done using Flow Cytometry Absolute Cell Count System.Result: Out of 150 patients 82 were male and 68 were female patients. The mean value for base line CD4 count for general group lies between those of female and male groups, with mean female (126.88cells/cmm) was lesser than that of male group (i.e. 141cells/cmm) indicating females were at higher risk of being Immunocompromised compare to males.  Also that the standard deviation of female (5.4) was lesser to male (48.43) supporting the above statement. After 6 months of antiretroviral therapy, the mean CD4 counts was in the relation 352.74 cells/cmm(Male) <378.82 cells/cmm(general) <410.26 cells/cmm (Female) with the standard deviation relation 162.68 (male) <179.49 (general) <194.46 (Female).Conclusion: The results of this study indicated that antiretroviral therapy plays an important role in maintaining the CD4cell counts and CD4 counts in female patients are much lower compared to the males and they respond well to therapy compared to the male population


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