Warthin like variant of Papillary carcinoma thyroid against the background of Hashimotos thyroiditis : a case report
Keywords:
Papillary thyroid carcinoma, Warthin-like variant of PTC.
Abstract
Papillary thyroid carcinoma (PTC) is the most common malignant neoplasm of the thyroid gland with many variants . The Warthin-like variant of PTC (WLPTC) is a rare accounting for 1-2% of PTC that is considered to be a subtype of the oncocytic variant. A 35-year-old female sought consult for assessment of a painless right neck tumor. Fine-needle aspiration biopsy report was given as hashimotos thyroiditis with hurthe cell neoplasm . The patient underwent right hemithyroidectomy. Grossly a single lobe of thyroid which was nodular on external surface and cut surface there was a single nodule measuring 1 cm in diameter,whitish in appearance with few areas of congestion. Microscopically, the tumor was composed of papillae lined by cells with eosinophilic cytoplasm, nuclear chromatin clearing, grooves, and pseudoinclusions and a characteristic lymphoplasmacytic infiltrate of the papillae cores. At places the thyroid parenchyma shows follicles of vaying sizes along with lymphoid follicles.References
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2. Yeo M N, Bae J S, Lee S, Kim M, Lim D. The Warthin-Like Variant of Papillary Thyroid Carcinoma:A Comparison with Classic Type in the Patients with Coexisting Hashimoto’s Thyroiditis, International Journal of Endocrinology 2015;1:34-36
3. Colunga K ,Solis A, Falcón L A, Quintana O A. Warthin-Like Papillary Thyroid Carcinoma Associated with Lymphadenopathy and Hashimoto's Thyroiditis. Case Rep Endocrinol. 2015;25:18-19
4. Paliogiannis P, Attene F, Trogu T, Trignano M .Warthin-Like Papillary Carcinoma of the Thyroid Gland:Case Reports in Oncological Medicine 2012:12;15-19
5. Robyn L, Sylvia L, LiVols S, Virginia A. Warthin-like Tumor" of the Thyroid ,American Journal of Surgical Pathology:1995:12:11-15
6. Rosai J. Rosai and Ackerman’s Surgical Pathology, Soft tissue. 10th ed. NewYork: Mosby Elsevier;2011.
Published
2016-08-04
Issue
Section
Case Report
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