Synchronous Tumors of Endometrium and Bilateral Fallopian Tubes: A Rare Case Report
Keywords:
Synchronous tumors, Fallopian tube, endometrium, primary, carcinoma
Abstract
Although the simultaneous presentation of endometrial and ovarian carcinomas of the endometrioid type is well described, little is known about a similar phenomenon involving the endometrium and fallopian tube . We present a rare case of synchronous primary endometrial and bilateral fallopian tubes carcinoma seen in the Department of Pathology at Santokba Durlabhji Hospital, Jaipur. Fallopian tube tumors that could have represented luminal extension of the endometrial carcinoma or that represented an unequivocal metastasis to the fallopian tube were excluded.References
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16. Herrinton LJ, Voigt LF, Weiss NS, Beresford SA, Wingo PA. Risk factors for synchronous primary endometrial and ovarian cancers. Ann Epidemiol 2011;11:529.
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19. Woodruff JD, Solomon D, Sullivant H. Multifocal disease in the upper genital canal. Obstet Gynecol 1985;65:695.
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21. Scully RE, Young RH, Clement PB. Tumors of the ovary, maldeveloped gonads, fallopian tube, and broad ligament. Atlas of tumor pathology. Bethesda, MD: Armed Forces Institute of Pathology. 1998.
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2. Barbara MN, Rochelle LG, Kimberly HA, Chris H. Jokinen, Lauren E. Kernochan, Catherine C. Pizzi. The Molecular Pathogenesis of Hereditary Ovarian Carcinoma: Alterations in the Tubal Epithelium of Women with BRCA1 and BRCA2 Mutations. Cancer 2010; 116(22): 5261–5271.
3. Jongsma APM, Piek JMJ, Zweemer RP, et al. Molecular evidence for putative tumour suppressor genes on chromosome 13q specific to BRCA1 related ovarian and fallopian tube cancer . J Clin Pathol: Mol Pathol 2002;55:305–309
4. Culton LK, Deavers MT, Silva EG, Liu J, Malpica A. Endometrioid carcinoma simultaneously involving the uterus and the fallopian tube: a clinicopathologic study of 13 cases. Am J Surg Pathol 2006; 30:844-9.
5. Wang H, Xiao SS, Zeng F. Synchronous primary endometrial and fallopian tube cancers: one case report. J South Med Univ 2011; 31(12):2093-4.
6. Eisner RF, Nieberg RK, Berek JS .Synchronous primary neoplasms of female reproductive tract.Gynecol Oncol 1989; 33:335.
7. Baekelandt M, Jorunn Nesbakken A, Kristensen GB, Trope CG, Abeler VM. Carcinoma of the fallopian tube. Cancer 2000;89:20-76.
8. Terzakis E, Androutsopoulos , Grigoriadis C, et al. Synchronous primary endometrial and fallopian tube cancers. Eur J Gynaecol Oncol 2010 ; 31(4) : 467-8.
9. Tong Seo-Yun , Sek Lee Yong,Park Jong Sup, et al.Clinical analysis of synchronous neoplasms of female reproductive tract .European Jrnl of Obs and Gyn and reproductive biology . 2008; 136: 78-82.
10. Parazini,La Vechia C,Bocciolone L et al.The epidemiology of endometrial cancer.Gynecol Oncol.1991;41:1-16
11. Eifel P, Hendrickson M, Ross J, Ballon S, Martinez A, Kempson R. Simultaneous presentation of carcinoma involving the ovary and the uterine corpus. Cancer 1982;50:163–70.
12. Lauchlan SC. The secondary Mu¨ llerian system. Obstet Gynecol Surv 1972;27:133–46.
13. Sica V, Nola E, Contieri E et al. Estradiol and progesterone receptors in malignant gastrointestinal tumors. Cancer Res 1984;44:4670–4.
14. Chiang YC, Chen CA , Huang CY, Hsieh CY, Cheng WF. Synchronous primary cancers of the endometrium and ovary . Int J Gynecol Cancer 2008; 18: 159–164
15. Kambi Deepthi P, Mallikarjuna M N, Santosh CS, Abhishek V. Synchronous malignancies of ovary, fallopian tube and cervix- A rare case. Intl J of Biomed and Adv Research 2013; 4:9.
16. Herrinton LJ, Voigt LF, Weiss NS, Beresford SA, Wingo PA. Risk factors for synchronous primary endometrial and ovarian cancers. Ann Epidemiol 2011;11:529.
17. Androutsopoulos G, Adonakis G, Tsamantas A, et al . Synchronous primary cancers in a woman with scleroderma:a case report.Euro J Gynaecol Oncol 2008 ;29:548.
18. Palm L, Marcus V, Gilbert L, Chong G, Foulkes WD. Synchronous occult cancers of the endometrium and fallopian tube in an MSH2 mutation carrier at time of prophylactic surgery.Gynecol Oncol 2008;111:575.
19. Woodruff JD, Solomon D, Sullivant H. Multifocal disease in the upper genital canal. Obstet Gynecol 1985;65:695.
20. Ulbright T, Roth L. Metastatic and independent cancers of the endometrium and ovary: a clinicopathologic study of 34 cases. Hum Pathol. 1985; 16 :28– 34.
21. Scully RE, Young RH, Clement PB. Tumors of the ovary, maldeveloped gonads, fallopian tube, and broad ligament. Atlas of tumor pathology. Bethesda, MD: Armed Forces Institute of Pathology. 1998.
22. Ree YS, Cho SH, Kim SR, et al. Synchronous primary endometrial and ovarian cancer with three different histologic patterns: a case report. Int J Gynecol Cancer. 2003, 13, 678–682.
Published
2016-08-24
Issue
Section
Case Report
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