A Rare Case of Renal Pelvis Urothelial Carcinoma In situ associated with Hydronephrosis and Atrophic Kidney
Keywords:
Urothelial carcinoma in situ, Atrophic kidney, Hydronephrosis, Renal stone
Abstract
Urothelial tumours involving the renal pelvis or ureter are relatively uncommon, accounting for about 5% to 7% of all renal tumours and about 5% of all urothelial tumours. Main risk factors for urothelial tumors include smoking, high tea intake and long term use of certain analgesic like phenacetin .Upper urinary tract urothelial tumors can be associated with renal stone disease or hydronephrosis but association is rare with only few case reports.Upper urinary tract tumors associated with renal stone and hydronephrosis are often missed in urine cytological examination and ultrasound. Therefore it is important to carefully examine the gross specimen and microscopy, keeping in mind the possibility of upper urinary tract tumors in such cases. Here we report a case of renal pelvis urothelial carcinoma in situ associated with hydronephrosis and atrophic kidney for its rarity.References
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13. Mazeman E. Tumours of the upper urinary tract calyces, renal pelvis and ureter. Eur Urol .1976; 2: 120–126.
14. Guinan P, Vogelzang NJ, Randazzo R, et al. Renal pelvic cancer: a review of 611 patients treated in Illinois 1975– 1985. Cancer Incidence and End Results Committee. Urology 1992; 40: 393–399
15. Kirkali Z, Tuzel E. Transitional cell carcinoma of the ureter and renal pelvis. Crit Rev Oncol Hematol. 2003; 47: 155–169.
16. Kalyan CL, Christopher RP. Treatment of Upper Tract Urothelial Carcinoma: A Review of Surgical and Adjuvant Therapy.Rev Urol.2006;8(2):61-70
2. Cheng L, Cheville JC, Neumann RM, Bostwick DG Natural history of urothelial dysplasia of the bladder m J Surg Pathol. 1999 Apr;23(4):443-7
3. Mallofré C , Castill M, Vanesa M, Manel S. Immunohistochemical Expression of CK20, p53, and Ki-67 as Objective Markers of Urothelial Dysplasia Mod Pathol. 2003;16(3):187–191
4. McLaughlin JK, Blot WJ, Mandel JS, et al. Etiology of cancer of the renal pelvis. J
Natl Cancer Inst. 1983; 71: 287–291.
5. Hui Y, Anthony S,Leong Y. Histologic Grading of Noninvasive Papillary Urothelial Tumor. Am J Clin Pathol. 2004;121(5)
6. Booth CM, Cameron KM, Pugh RC. Urothelial carcinoma of the kidney and ureter. Br J Urol 1980; 52: 430–435.
7. McCarron JP, Mills C, Vaughn ED Jr. Tumors of the renal pelvis and ureter: current concepts and management.Semin Urol.1983; 1: 75–81.
8. Bennington JL, Beckwith JB. Atlas of tumor pathology, second series, fascicle 12, tumors of the kidney, renal pelvis, and ureter. Armed Forces Institute of Pathology. United States Government Press 1975
9. McCarron JP Jr, Chasko SB, Gray GF Jr. Systematic mapping of nephroureterectomy specimens removed for urothelial cancer: pathological findings and clinical correlations. J Urol. 1982; 128: 243–246.
10. Heney NM, Nocks BN, Daly JJ, et al. Prognostic factors in carcinoma of the ureter. J Urol. 1981; 125: 632–636.
11. Nocks BN, Heney NM, Daly JJ, et al. Transitional cell carcinoma of renal pelvis. Urology 1982; 19: 472–477.
12. Nielsen K, Ostri P. Primary tumors of the renal pelvis: evaluation of clinical and pathological features in a consecutive series of 10 years. J Urol.1988; 140: 19–21.
13. Mazeman E. Tumours of the upper urinary tract calyces, renal pelvis and ureter. Eur Urol .1976; 2: 120–126.
14. Guinan P, Vogelzang NJ, Randazzo R, et al. Renal pelvic cancer: a review of 611 patients treated in Illinois 1975– 1985. Cancer Incidence and End Results Committee. Urology 1992; 40: 393–399
15. Kirkali Z, Tuzel E. Transitional cell carcinoma of the ureter and renal pelvis. Crit Rev Oncol Hematol. 2003; 47: 155–169.
16. Kalyan CL, Christopher RP. Treatment of Upper Tract Urothelial Carcinoma: A Review of Surgical and Adjuvant Therapy.Rev Urol.2006;8(2):61-70
Published
2016-08-24
Issue
Section
Case Report
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