https://www.pacificejournals.com/journal/index.php/apalm/issue/feed Annals of Pathology and Laboratory Medicine 2019-01-20T17:18:50+00:00 Dr. Prashant Goyal editor.apalm@gmail.com Open Journal Systems <p><strong>Annals of Pathology and Laboratory Medicine (APALM)</strong> is an international, Double-blind peer-reviewed, indexed, open access, online and print journal&nbsp;for pathologists, microbiologist, biochemist and clinical laboratory scientists,&nbsp;with <strong>Index Copernicus (IC) Value (ICV 2016): 74.20, </strong>and <strong>DOI: 10.21276/APALM&nbsp;</strong>being&nbsp;published by&nbsp;<a title="PaGe" href="/" target="_blank" rel="noopener">'</a><strong><a title="PaGe" target="_blank"><strong>Pacific group of e-Journals</strong>' (<strong>PaGe</strong>)</a>, </strong>an&nbsp;<em>ISO 9001:2008</em> Certified&nbsp;academic publishing house.</p> <p>APALM is a specialized journal, which publishes original, peer-reviewed articles&nbsp;in the field of Pathology and Laboratory Medicine which, <em>inter alia</em>, includes Histopathology, Cytopathology, Hematology, Clinical Pathology, Forensic Pathology, Blood Banking, Clinical Bio-Chemistry, Medical Microbiology (Bacteriology, Virology, Mycology, Parasitology), etc.</p> <p>APALM was set up in 2014 and has been successfully<strong>&nbsp;indexed</strong>&nbsp;with following renowned Indexing and Abstracting<strong>&nbsp;</strong>databases:</p> <div dir="ltr" style="text-align: left;"> <table class="MsoTableGrid" style="border-collapse: collapse; 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text-align: center;"><a style="margin-left: 1em; margin-right: 1em;" href="https://1.bp.blogspot.com/-VAQYsxP3Vg0/VkMfKROZQ4I/AAAAAAAAAg8/zmx0IVJOEEA/s1600/International%2Bimpact%2Bfactor%2BJournals.png"><img src="https://1.bp.blogspot.com/-VAQYsxP3Vg0/VkMfKROZQ4I/AAAAAAAAAg8/zmx0IVJOEEA/s1600/International%2Bimpact%2Bfactor%2BJournals.png" alt="" border="0"></a></div> <div class="MsoNormal" style="background: #FBFBF3; line-height: 15.0pt; margin-left: 18.0pt; mso-margin-bottom-alt: auto; mso-margin-top-alt: auto; text-align: center;" align="center"><span style="color: #111111; font-family: 'arial' , sans-serif; font-size: 9.0pt;">International Impact Factor Services (IIFS)</span></div> </td> </tr> <tr> <td style="border-top: none; border: solid windowtext 1.0pt; mso-border-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0cm 5.4pt 0cm 5.4pt;"> <div class="MsoNormal" style="background: #FBFBF3; line-height: 15.0pt; margin-left: 18.0pt; mso-margin-bottom-alt: auto; mso-margin-top-alt: auto; text-align: center;" align="center"><span style="color: #111111; font-family: 'arial' , sans-serif; font-size: 9.0pt;">Index Scientific Journals (ISJ)</span></div> </td> <td style="border-bottom: solid windowtext 1.0pt; border-left: none; border-right: solid windowtext 1.0pt; border-top: none; mso-border-alt: solid windowtext .5pt; mso-border-left-alt: solid windowtext .5pt; mso-border-top-alt: solid windowtext .5pt; padding: 0cm 5.4pt 0cm 5.4pt;"> <div class="MsoNormal" style="background: #FBFBF3; line-height: 15.0pt; margin-left: 18.0pt; mso-margin-bottom-alt: auto; mso-margin-top-alt: auto; text-align: center;" align="center"><span style="color: #111111; font-family: 'arial' , sans-serif; font-size: 9.0pt;">Journal Index</span></div> </td> </tr> </tbody> </table> </div> https://www.pacificejournals.com/journal/index.php/apalm/article/view/2118 Immunocytochemistry as An Adjunctive Diagnostic Tool in Cytology 2019-01-20T17:04:08+00:00 Swati Bhardwaj swat.bhardwaj@yahoo.com Charanjeet Ahluwalia charanjeet.ahluwalia@rediffmail.com Mukul Singh drmukulsingh@gmail.com Sachin Kolte drsachinkolte@gmail.com Neha Madan nehakawatramadan@gmail.com Rashmi Arora drarorarashmi@gmail.com Indrani Dhawan indranidhawan@gmail.com <p><strong>Background:</strong></p> <p>Cytology is rapidly progressing from a primary screening investigation to a definitive diagnostic modality in increasing number of cases. This has been made possible by the use of ancillary tests such as immunochemistry, and molecular techniques. Over the years, the use of immunochemistry has evolved from being just an adjunct to diagnosis, to determining primary site of malignancy and exact typing of malignancies.</p> <p>This study was conducted to find out the impact of immunochemistry performed on cell blocks and smears of varied cytology material including FNAC material and fluids.</p> <p><strong>Methods:</strong></p> <p>It was a retrospective study. All cytology cases including FNAC material and fluids on which immunochemistry had been performed were retrieved from records. Immunochemistry was performed manually on cold acetone fixed smears, and cell-block preparations.</p> <p><strong>Result:</strong></p> <p>A total of 50 cases were evaluated from past two years, including 10 cases of fluids, and 40 cases of FNAC material. Staining was done on cell blocks in 44 cases, and on smears in 6 cases. In 15 cases, immunochemistry was performed to find out the site of primary malignancy, of which in 11 cases, it was positively contributory in giving a list of possible primaries and in 4 cases, single definitive diagnosis was provided. In 27 cases, it helped in typing of malignancies, and providing additional information. It was non-contributory in 8 cases.</p> <p><strong>Conclusion: </strong></p> <p>Immunochemistry, on smears as well as cell blocks is a useful adjunctive tool in cytology, therefore, it is advised to perform immunochemistry wherever possible.</p> 2019-01-20T17:04:08+00:00 ##submission.copyrightStatement## https://www.pacificejournals.com/journal/index.php/apalm/article/view/2200 A Histomorphological Study of Vesiculobullous Lesions of Skin 2019-01-20T17:18:50+00:00 Chakor Makarand Rokde drchakor11@gmail.com Rajshri P Damle rajshriborase@gmail.com N V Dravid mapcon2011@gmail.com <p><strong>Background:</strong> <br>Vesiculobullous disorders are a complex group of disorders which continue to be an enigma. Wide variety of pathological processes can lead to development of Vesiculobullous eruptions over the body. They may occur in many dermatoses which include various inflammatory, infective, autoimmune, drug induced as well as genetic conditions.</p> <p>Each entity of vesiculobullous lesion has similar or confusing clinical features but different histopathological morphology. Histopathological examination is helpful in definitive diagnosis of vesiculobullous disorder which is very essential for specific treatment and an appropriate desirable outcome.</p> <p><strong>Aim:</strong><br>To study and classify various vesiculobullous lesions of the skin in various categories.</p> <p>&nbsp;<strong>Material and Method:</strong><br>A prospective observational study of vesiculobullous lesions of the skin biopsies of 93 cases were received to the department of pathology over a period of 3 years. Complete clinical and relevant history was recorded. The specimens were routinely processed and haematoxylin and eosin stained slides were studied.</p> <p><strong>Result:</strong> <br>A total of 93 cases of vesiculobullous lesions of the skin were diagnosed. Among these lesions, Pemphigus vulgaris were seen in 34 (36.55%) cases, Bullous pemphigoid in 22(22.65%) cases of and spongiotic dermatosis in 14 (15.05%) cases. The maximum numbers of cases (32.25%) were in 4<sup>th</sup> to 5<sup>th</sup> decades.</p> <p><strong>Conclusion</strong>: <br>Thorough histopathological workup and clinical correlation is essential to confirm diagnosis of vesiculobullous lesions of skin.</p> 2019-01-20T17:18:50+00:00 ##submission.copyrightStatement##