Annals of Pathology and Laboratory Medicine 2022-06-29T18:27:02+00:00 Dr. Prashant Goyal Open Journal Systems <p><strong>Annals of Pathology and Laboratory Medicine (APALM)</strong> is an international, Double-blind peer-reviewed, indexed, open access, online and print journal&nbsp;for pathologists, microbiologist, biochemist and clinical laboratory scientists, and is published by <strong><a href="" target="_blank" rel="noopener"><strong>Pacific group of e-Journals</strong>' (<strong>PaGe</strong>)</a>, </strong>an&nbsp;<em>ISO 9001:2008</em> Certified&nbsp;academic publishing house.</p> <p>Set up in 2014, APALM is a specialized journal, which publishes original, peer-reviewed articles&nbsp;in the field of Pathology and Laboratory Medicine which, <em>inter alia</em>, includes Histopathology, Cytopathology, Hematology, Clinical Pathology, Forensic Pathology, Blood Banking, Clinical Bio-Chemistry, Medical Microbiology (Bacteriology, Virology, Mycology, Parasitology), etc.</p> <p><strong>DOI: 10.21276/APALM (<a title="Verify APALM DOI " href="" target="_blank" rel="noopener"></a>)<br></strong></p> <p>&nbsp;</p> Erythrocyte Sedimentation Rate (with its inherent limitations) Remains a Useful Investigation in Contemporary Clinical Practice 2022-06-29T18:27:01+00:00 Manoj A Kahar <p>Erythrocyte Sedimentation Rate(ESR) determined by Westergren method is used in diagnosis and monitoring inflammatory activities. Extremely elevated ESR (&gt;100mm/hr) is usually indicative of a serious underlying disease. ESR phenomenon occurs in three phases (Aggregation, Decantation &amp; Packaging) and is related to certain laws of physics like Stokes’s law. ESR by Westergren method is affected by RBC, Plasma and Technical factors and also by many physiological and clinical states. ESR by Westergren method is endorsed by International Council for Standardization in Haematology as a “Gold Standard” for ESR determination and provides recommendations to perform ESR by reference method. ESR by conventional Westergren method has many limitations necessitating technical innovations and alternate test methods in ESR determination.</p> 2022-06-29T18:26:26+00:00 ##submission.copyrightStatement##