Annals of Pathology and Laboratory Medicine https://www.pacificejournals.com/journal/index.php/apalm <p><strong>Annals of Pathology and Laboratory Medicine (APALM)</strong> is an international, Double-blind peer-reviewed, indexed, open access, online and print journal&nbsp;for pathologists, microbiologist, biochemist and clinical laboratory scientists, and is published by <strong><a href="https://www.pacificejournals.com" target="_blank" rel="noopener"><strong>Pacific group of e-Journals</strong>' (<strong>PaGe</strong>)</a>, </strong>an&nbsp;<em>ISO 9001:2008</em> Certified&nbsp;academic publishing house.</p> <p>Set up in 2014, APALM is a specialized journal, which publishes original, peer-reviewed articles&nbsp;in the field of Pathology and Laboratory Medicine which, <em>inter alia</em>, includes Histopathology, Cytopathology, Hematology, Clinical Pathology, Forensic Pathology, Blood Banking, Clinical Bio-Chemistry, Medical Microbiology (Bacteriology, Virology, Mycology, Parasitology), etc.</p> <p><strong>DOI: 10.21276/APALM (<a title="Verify APALM DOI " href="https://dx.doi.org/10.21276/apalm" target="_blank" rel="noopener">https://dx.doi.org/10.21276/apalm</a>)<br></strong></p> <p>Index Copernicus (IC) Value (ICV 2016): 74.20</p> en-US <p>Authors who publish with this journal agree to the following terms:</p> <ol> <li class="show">Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a&nbsp;<a href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License</a>&nbsp;that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.</li> <li class="show">Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.</li> <li class="show">Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See&nbsp;The Effect of Open Access at http://opcit.eprints.org/oacitation-biblio.html).</li> </ol> <p>&nbsp;</p> editor.apalm@gmail.com (Dr. Prashant Goyal) contactus@pacificejournals.com (Amit Saggar) Fri, 24 May 2019 18:18:37 +0000 OJS 3.1.1.2 http://blogs.law.harvard.edu/tech/rss 60 Cytomorphological Study of Palpable Soft Tissue Tumors by Fine Needle Aspiration Cytology https://www.pacificejournals.com/journal/index.php/apalm/article/view/2293 <p><strong>Background:</strong> Soft tissue tumors are a highly heterogeneous group of tumors that are classified by the line of differentiation, according to the adult tissue they resemble. Objective of this study was to assess the utility of fine needle aspiration cytology (FNAC) in diagnosing soft tissue tumors and to do the histo-pathological correlation wherever possible.</p> <p><strong>Methods</strong>: Conventional May-Grunwald Giemsa (MGG) staining was done in all the 100 cases and cytodiagnosis was rendered. Histopathology was available in 41 cases. The cytological diagnosis was correlated with histology in these cases. The accuracy rate, sensitivity, specificity, the positive and negative predictive value were calculated. P value was found by applying Fisher’s exact test.</p> <p><strong>Results:</strong> The study was carried out on aspirates of 100 patients. Out of which 65 cases were benign, 30 were malignant while 5 cases were inadequate. Lipoma was the most common cytologically diagnosed benign lesion. Dermatofibrosarcoma protuberans (DFSP) and synovial sarcoma were found to be the most common malignant soft tissue tumors. Cyto-histological correlation could be achieved in 41 cases, with an accuracy of 92.7%.</p> <p><strong>Conclusion: </strong>FNAC is a well-tolerated and cost-effective procedure. It provides predictive diagnosis of benign or malignant soft tissue tumors and also specific tumor type, especially after correlation with clinical and radiological findings.</p> Mamta Dwivedi, Deepa Rani, Anjani Kumar Tripathi, Rohan Sirohi, Atul Gupta, Aradhana Singh ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 https://www.pacificejournals.com/journal/index.php/apalm/article/view/2293 Fri, 24 May 2019 18:19:02 +0000 Comparison of Histopathological Features of ‘Incidental’ and ‘Non-Incidental’ Papillary Thyroid Microcarcinomas https://www.pacificejournals.com/journal/index.php/apalm/article/view/2296 <p><strong>Background: </strong>Papillary thyroid microcarcinoma (Pm) is defined as a papillary carcinoma with size ≤ 10mm. On clinical and histological grounds, there are two presentations-‘incidental’ and ‘non-incidental’. Histopathological parameters like intratumoral/peritumoral fibrosis, multifocality, infiltrative borders, subcapsular location, lymphovascular emboli and histological type have been introduced in the reporting of Pm, besides the size which is considered an important prognostic/risk factor.</p> <p><strong>Methods: </strong>The present study is a 5-year retrospective comparative study between the Pm which were incidentally detected, and those which had been previously diagnosed on fine needle aspiration/radiology or clinically suspicious of Pm.</p> <p><strong>Result: </strong>The number of cases in both incidental (111) and non-incidental (110) Pm have been found to be comparable in the present study, which is attributable to meticulous grossing and extensive sampling of all thyroidectomy specimen. Size and multifocality has been significantly different between incidental and non-incidental Pm (p-value &lt;0.05). The parameters like intratumoral/peritumoral fibrosis, infiltrative border and subcapsular location were significantly higher in larger sizes (&gt;5mm) of non-incidental Pm (p-value &lt;0.05). These parameters, however, were not found to be significant when analysed individually or with one another, between the two groups (p-value &gt;0.05). In the incidental Pm of size ≤ 5mm, a good proportion of cases show these parameters, implicating their importance for further follow-up.</p> <p><strong>Conclusion: </strong>Size and focality has been found to differ between incidental and non-incidental Pm. The histological parameters defined for Pm need to be followed up for a longer period to identify the prognostic significance, and their role in the different manifestation of incidental and non-incidental Pm.</p> Abhijit Kalita, Annie Jojo, Smitha NV ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 https://www.pacificejournals.com/journal/index.php/apalm/article/view/2296 Fri, 24 May 2019 18:24:07 +0000