Management of Patent Ductous Arteriosus: a short review
Keywords:
Non-steroidal anti-inflammatory drugs, Patent ductus arteriosus, Prostaglandins,
Abstract
Patent ductus arteriosus (PDA) is one of the most common congenital heart defects. Failure of the ductus arteriosus (DA) to close within 72 hours after birth result in PDA. Clinical signs of ductal patency are murmur, tachycardia, bounding peripheral pulses, and congestive heart failure . Complications of a persistently patent DA after birth are heart failure, renal dysfunction, necrotizing enterocolitis (NEC) and altered postnatal nutrition and growth. Also risk of developing of chronic lung disease .Pharmacologic closure can be done by administration of intravenous indomethacin or ibuprofen .Other management strategies are cath intervention, and surgical ligation.References
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12. VanOvermeire B, Chemtob S. The pharmacologic closure of the patent ductus arteriosus. Semin Fetal Neonatal Med. 2005;10:177–184. [PubMed]
13. Malviya M, Ohlsson A, Shah S. Surgical versus medical treatment with cyclooxygenase inhibitors for symptomatic patent ductus arteriosus in preterm infants. Cochrane Database of Systematic Reviews. 2003. Art. No.:CD003951. DOI: 10.1002/14651858.CD003951. [PubMed]
14. Kabra NS, Schmidt B, Roberts RS. Neurosensory impairment after surgical closure of patent ductus arteriosus in extremely low birth weight infants: results from the Trial of Indomethacin Prophylaxis in Preterms. J Pediatr. 2007;150:229–234. et al. [PubMed]
15. Koehne PS, Bein G, Alexi-Meskhishvili V. Patent ductus arteriosus in very low birthweight infants: complications of pharmacological and surgical treatment. J Perinat Med. 2001;29:327–334. et al. [PubMed]
16. Clyman RI. Ibuprofen and patent ductus arteriosus. New Engl J Med. 2000;343:728–739. [PubMed]
2. Hajjar ME, Vaksmann G, Rakza T. Severity of the ductal shunt: a comparison of different markers. Arch Dis Child Fetal Neonatal Ed. 2005;90:F419–F422. et al. [PMC free article] [PubMed]
3. Miao CY, Zuberbuhler JS, Zuberbuhler JR. Prevalence of congenital cardiac anomalies at high altitude. J Am Coll Cardiol. 1990;12:224–228. [PubMed]
4. Nora JJ, Nora AH. Recurrence risks in children having one parent with a congenital heart disease. Circulation. 1976;53:701–702. [PubMed]
5. Gittenberger-de Groot AC, Moulaert AJ, Hitchcock JF. Histology of the persistent ductus arteriosus in cases of congenital rubella. Circulation. 1980;62:183–186. [PubMed]
6. Pegoli W. Pericardium and great vessels. In: Oldham KT, Colombiani PM, editors. Principles and Practice of Pediatric Surgery. 4th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2005. p. 1019. et al., editors.
7. Moore P, Brook MM, Heyman MA. Patent ductus arteriosus. In: Allen HD, Gutgesell HP, editors. Moss & Adams' Heart Disease in Infants, Children & Adolescents: Including the Fetus and Young Adults. 6th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2001. pp. 653–663. et al., eds.
8. Zipes DP, Libby P, editors. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 7th ed. Philadelphia, PA: Elsevier Saunders; 2005. Patent ductus arteriosus; pp. 1511–1513. et al., eds.
9. Aranda JV, Thomas R. Intravenous ibuprofen for preterm infants. NeoReviews. 2005;6:e516–e523.
10. Mosca F, Bray M, Lattanzio M. Comparative evaluation of the effects of indomethacin and ibuprofen on cerebral perfusion and oxygenation in preterm infants with patent ductus arteriosus. J Pediatr. 1997;131:549–554. et al. [PubMed]
11. Pezzati M, Vagni V, Biagiotti R. Effects of indomethacin and ibuprofen on mesenteric and renal blood flow in preterm infants with patent ductus arteriosus. J Pediatr. 1999;135:733–738. et al. [PubMed]
12. VanOvermeire B, Chemtob S. The pharmacologic closure of the patent ductus arteriosus. Semin Fetal Neonatal Med. 2005;10:177–184. [PubMed]
13. Malviya M, Ohlsson A, Shah S. Surgical versus medical treatment with cyclooxygenase inhibitors for symptomatic patent ductus arteriosus in preterm infants. Cochrane Database of Systematic Reviews. 2003. Art. No.:CD003951. DOI: 10.1002/14651858.CD003951. [PubMed]
14. Kabra NS, Schmidt B, Roberts RS. Neurosensory impairment after surgical closure of patent ductus arteriosus in extremely low birth weight infants: results from the Trial of Indomethacin Prophylaxis in Preterms. J Pediatr. 2007;150:229–234. et al. [PubMed]
15. Koehne PS, Bein G, Alexi-Meskhishvili V. Patent ductus arteriosus in very low birthweight infants: complications of pharmacological and surgical treatment. J Perinat Med. 2001;29:327–334. et al. [PubMed]
16. Clyman RI. Ibuprofen and patent ductus arteriosus. New Engl J Med. 2000;343:728–739. [PubMed]
Published
2016-10-27
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