Molluscum Contagiosum of Areola
Keywords:
Areola, Molluscum contagiosum, Histopathology, Cytology
Abstract
Molluscum contagiosum is an extremely contagious under-reported viral infection of the skin and occasionally of the mucous membranes which is caused by a double-stranded DNA poxvirus called the molluscum contagiosum virus. Molluscum contagiosum lesions are typically flesh-colored, dome-shaped, and pearly in appearance. Any area of the body can be infected by this virus, however most commonly involved parts are the face, trunk, arms, groin, and the legs. The areola and nipple are very rare locations to develop molluscum contagiosum. We herein describe an unusual case of molluscum contagiosum of the right areola in a 48-year-old woman and review the various clinicopathological characteristics of this ubiquitous condition.References
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28. Tyring SK. Molluscum contagiosum: the importance of early diagnosis and treatment. Am J Obstet Gynecol 2003;189 (3 Suppl): S12–6.
2. Hanson D, Diven DG. Molluscum contagiosum. Dermatol Online J. 2003;9(2): 2.
3. Bateman F: Molluscum contagiosum. In: Shelley WB, Cressey JT, editors. Classics in Dermatology. Springfield, Charles C. Thomas: 1953;20.
4. Brown ST, Nalley JF, Kraus SJ. Molluscum contagiosum. Sex Transm Dis. 1981;8(3):227 -34.
5. Juliusberg M. Zur Kenntnis des virus des Molluscum contagiosum. Dtsch Med Wochenschr. 1905;31:1598-99.
6. Vos T, Flaxman AD, Naghavi M, Lozano R, Michaud C, Ezzati M, et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380 (9859): 2163-96.
7. Smith KJ, Yeager J, Skelton H. Molluscum contagiosum: its clinical, histopathologic, and immunohistochemical spectrum. Int J Dermatol. 1999;38(9):664-72.
8. Oppedal BR. Molluscum contagiosum diagnosed in a cytologic smear. Acta Cytol. 1985; 29(3): 501.
9. Smith KJ, Skelton H. Molluscum contagiosum: recent advances in pathogenic mechanisms, and new therapies. Am J Clin Dermatol. 2002;3(8):535-45.
10. Schmid-Wendtner MH, Rütten A, Blum A. Flat rapidly growing tumor in a 20-year-old woman. Hautarzt. 2008;59(10):838-40.
11. Carvalho G. Molluscum contagiosum in a lesion adjacent to the nipple. Report of a case. Acta Cytol. 1974;18(6):532-4.
12. Kumar N, Okiro P, Wasike R. Cytological diagnosis of molluscum contagiosum with an unusual clinical presentation at an unusual site. J Dermatol Case Rep. 2010;4(4):63-5.
13. Parlakgumus A, Yildirim S, Bolat FA, Caliskan K, Ezer A, Colakoglu T, et al. Dermatoses of the nipple. Can J Surg. 2009;52(2):160-1.
14. Schornack MM, Siemsen DW, Bradley EA, Salomao DR, Lee HB. Ocular manifestations of molluscum contagiosum. Clin Exp Optom. 2006;89(6):390-3.
15. Vardhan P, Goel S, Goyal G, Kumar N. Solitary giant molluscum contagiosum presenting as lid tumor in an immunocompetent child. Indian J Ophthalmol. 2010;58(3):236-8.
16. Cohen PR, Tschen JA. Plantar molluscum contagiosum: a case report of molluscum contagiosum occurring on the sole of the foot and a review of the world literature. Cutis. 2012;90(1):35-41.
17. de Carvalho CH, de Andrade AL, de Oliveira DH, Lima Ed, da Silveira EJ, de Medeiros AM. Intraoral Molluscum contagiosum in a young immunocompetent patient. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012;114(1):e57-60.
18. Basta-Juzbašić A, Čeović, R. "Chancroid, lymphogranuloma venereum, granuloma inguinale, genital herpes simplex infection, and molluscum contagiosum". Clinics in Dermatology (Review). 2014;32 (2):290-8.
19. Likness LP. Common dermatologic infections in athletes and return-to-play guidelines. J Am Osteopath Assoc. 2011;111(6): 373-9.
20. Bandino JP, Wohltmann WE, Hivnor CM. What is your diagnosis? Giant molluscum contagiosum. Cutis. 2011;88(4):164,170-2.
21. Chen X, Anstey AV, Bugert JJ. Molluscum contagiosum virus infection. Lancet Infect Dis. 2013;13(10): 877-88.
22. Gupta RK, Naran S, Lallu S, Fauck R. Cytologic diagnosis of molluscum contagiosum in scrape samples from facial lesions. Diagnostic Cytopathol. 2003;29(2):84.
23. Jain S, Das DK, Malhotra V, Tatke M, Kumar N. Molluscum contagiosum. A case report with fine needle aspiration cytologic diagnosis and ultrastructural features. Acta Cytol. 2000;
44:63-6.
24. Hoyt BS, Tschen JA, Cohen PR. Molluscum contagiosum of the areola and nipple: case report and literature review. Dermatol Online J. 2013;19(7):18965.
25. Griffith RD, Yazdani Abyaneh MA, Falto-Aizpurua L, Nouri K. Pulsed dye laser therapy for molluscum contagiosum: a systematic review. J Drugs Dermatol. 2014;13(11): 1349-52.
26. Brown M, Paulson C, Henry SL.Treatment for anogenital molluscum contagiosum. Am Fam Physician. 2009;80(8): 864.
27. Brown J, Janniger CK, Schwartz RA, Silverberg NB. Childhood molluscum contagiosum. Int J Dermatol. 2006;45(2):93-9.
28. Tyring SK. Molluscum contagiosum: the importance of early diagnosis and treatment. Am J Obstet Gynecol 2003;189 (3 Suppl): S12–6.
Published
2016-12-22
Issue
Section
Case Reports
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