Lactational changes masquerading features of malignancy in breast: A Case Report
Keywords:
Lactation, young age, breast carcinoma
Abstract
Introduction: Pregnancy associated breast cancer is defined as "The diagnosis of breast cancer is made during pregnancy or within one year afterward." The incidences of breast carcinoma are 1 in 3000 pregnancy in west. Risk is increasing because of increased number of late pregnancies. Young age, lactating breast (dense) and paucity of incidences not only delay but confuse the pathologist for accurate diagnosis.Case report A 28 year lactating female with 2 months old baby, presented with breast lump. Lump was mobile, non-tender and of size 2x1 cm since 3 months and gradually increasing in size. On USG, it was benign. On FNAC, aspirate was milky mixed with blood, showing monotonous cells with abundant cytoplasm, bland nuclei in a secretary background. Final diagnosis was lactational changes in breast. After six months, lady came back with previous lump which was increased in size up to 6X5 cm. On FNAC, smear was having bizarre cells, reported as malignant and confirmed on histopathology. Patient was responded to chemotherapy and lump reduced in size.Conclusion: Pregnancy associated breast cancer is on rise. High grade of suspicion and complete evaluation including trucut biopsy will lead to correct diagnosis. DOI: 10.21276/AWCH.1806References
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2. Middleton L, Amin M, Gwyn K, et al. Breast carcinoma in pregnant women-assessment of clinicopathologic and immunohistochemical features. Cancer 2003;98(5):1055–60.
3. Anderson BO, Petrek JA, Byrd D, et al. Pregnancy influences breast cancer stage at diagnosisin women 30 years of age and younger. Ann SurgOncol 1996;3(2):204–11.
4. Ishida T, Yokoe T, Kasumi F, et al. Clinicopathologic characteristics and prognosis of breastcancer patients associated with pregnancy and lactation: analysis of case-control study inJapan. Jpn J Cancer Res 1992;83:1143–9.
5. Woo JC, Taechin Y, Hurd T. Breast cancer in pregnancy- a literature review. Arch Surg 2003;138:91–9.
6. Antonelli NM, Dotters DJ, Katz VL, Kuller JA. Cancer in pregnancy: A review of the literature- Part I. ObstetGynecolSurv 1996;51:125-34
7. Bonnier P, Romain S, Dilhuydy JM, et al. Influence of pregnancy on the outcome of breastcancer: a case–control study. Int J Cancer 1997;72:720–7.
8. Baker TP, Lenert JT, Parker J, et al. Lactating adenoma: a diagnosis of exclusion. Breast J 2001;7:354–7.
9. Cheek JH. Cancer of the breast in pregnancy and lactation. Am J Surg 1973;126:729-31.
10. Geschicker CF, Lewis D. Pregnancy and lactation changes in fibro-adenoma of the breast. BMJ 1938;1:499–503.
Published
2017-12-15
Issue
Section
Case Reports
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