Congenital Granular Cell Tumor in an Infant: a case report
Keywords:
Congenital Granular Cell Tumor, Granular Cell Fibroblastoma, Gingival Of The Anterior Alveolar Ridge, Polypoidal, Histopathology,
Abstract
Congenital granular cell tumor (CGCT) is a rare, benign soft tissue tumor seen in newborns.The tumor is quite uncommon, with an incidence of only 0.0006% and less than 250 cases have been reported in the literature so far. The lesion has a marked female preponderance, with the female:male ratio being 8-10:1. It usually occurs on the gingival of the anterior alveolar ridge, more frequently in the maxillary alveolus than in the mandibular alveolus.In this case report, we present a congenital granular cell tumor, sent by a paediatric surgeon as histopathological tissue from the oral cavity of 1 day old male baby, delivered with a solitary polypoidal nodule projecting from the mouth and presenting as difficulty in breast feeding. The mass was sent in toto and was diagnosed on histopathological examination.References
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2. Zerener T, Sencimen M, Altun C, Altug H. Congenital granular cell tumor in newborn. European Journal of Dentistry. 2013;7(4):497.
3. Conrad R, Perez M. Congenital Granular Cell Epulis. Archives of Pathology & Laboratory Medicine. 2014;138(1):128-131.
4. Kumar R, Jaiswal S, Singhal A, Garg R. Congenital granular cell lesion: A rare tumor of new born. Journal of Oral and Maxillofacial Pathology. 2013;17(3):440.
5. Fister P, Volavsek M, Novosel Sever M, Jazbec J. A newborn baby with a tumor protruding from the mouth. Acta Dermatovenerol Alp Panonica Adriat 2007;16(3):128‒30.
6. Mcguire TP. Gomes PP, Freilich MM, Sandor GKB. Congenital Epulis: A Surprise in the Neonate. J Can Dent Assoc 2006; 72(8):747-50.
7. Weiss SW, Goldblum JR. Enzinger & Weiss’s Soft Tissue Tumors. 5th ed. Philadelphia, PA: Mosby-Elsevier; 2008:878–889.
8. Eghbalian F, Monsef A. Congenital epulis in the newborn, review of the literature and a case report. J Pediatr Hematol Oncol. 2009;31(3):198–199.
9. Koch BL, Myer C 3rd, Egelhoff JC. Congenital epulis. AJNR Am J Neuroradiol 1997; 18(4):739–41.
10. Silva GCC, Vieira TC, Vieira JC, Martins CR, Silva EC. Congenital granular cell tumor (congenital epulis): A lesion of multidisciplinary interest. Med Oral Patol Oral Cir Bucal. 2007 Oct 1;12(6):428-30.
11. Lapid O, Shaco-Levy R, Krieger Y, Kachko L, Sagi A. Congenital Epulis. PEDIATRICS. 2001;107(2):e22-e22.
12. Dash JK, Sahoo PK, Das SN. Congenital granular cell lesion congenital epulis – report of a case. J Indian Soc Pedod Prev Dent 2004;22(2):63–7.
13. Regezi JA, Sciubba JJ, Pogrel MA. Atlas of Oral and Maxillofacial Pathology. Philadelphia, PA: WB Saunders; 2000:66.
14. Wenig BM. Atlas of Head and Neck Pathology. 2nd ed. Philadelphia, PA: Saunders-Elsevier; 2008:289–290.
15. Ugras S, Demirtas I, Bekerecioglu M, Kutluhan A, Karakok M, Peker O. Immunohistochemical study on histogenesis of congenital epulis and review of the literature. Pathol Int 1997;47(9):627–32.
16. Gokhale UA, Malhotra CJ. Congenital epulis of the newborn. Indian J Pathol Microbiol 2009; 52(3):436‒7.
Published
2016-02-07
Issue
Section
Case Reports
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