Correlation of Nutritional Status and Pressure Ulcers Healing in Spinal Cord Injury Subjects

A Non-randomized, Non-controlled Quasi Experimental Study

  • Amit Kumar Bhagat King George's Medical University
  • Rajeshwar Nath Srivastava King George’s Medical University, Lucknow, U.P., India
  • Mukesh Kumar Dwivedi King George's Medical University
  • Sudeepti Ratan Srivastava King George’s Medical University, Lucknow, U.P., India
  • Saloni Raj King George's Medical University
  • Abhijit Chandra King George's Medical University
Keywords: Pressure ulcer, Spinal cord injury, Nutritional biomarkers


Objective: This study was done to determine the cause effect relationship between pressure ulcers (PUs) and metabolic alterations in individual having PUs with Spinal Cord Injury (SCI) Methods: 123 SCI subjects with PUs were enrolled in the study. PUs were measured for surface area, exudate, depth and formation of granulation tissue using the pressure ulcers scale for healing tool. The nutritional status of subjects was assessed by measuring serum haemoglobin, albumin and transferrin levels at baseline (week 0), weeks 3 and 6 during follow-up. Results: An inverse correlation of wound size was observed with nutritional status at weeks 3 and 6. There was a significant increase (p < 0.001) in: Haemoglobin (10.7 - 12.4 g/dl), Albumin (2.9 - 4.04 g/dl) and Transferrin (174.1 - 186.9 μg/dl) levels at the time of discharge. The size of PUs was drastically reduced up to 5.4 fold at the time of discharge.  Conclusion: Given the high prevalence of malnutrition among subjects with PUs, performing a routine nutritional screening should result in early identification of residents with the risk of developing PUs. This article gives statistical evidence that healing of PUs is associated with an increase in Hb level and improving metabolic alterations. There seems to be a positive relationship between PU healing cascade and nutritional corrections. In future, this relation may be disclosed with newer intervention.   


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Original Article