Histopathological Lesions of Nasal Cavity, Paranasal Sinuses and Nasopharynx

  • Janice Jaison MIMER Medical College, Talegaon Dabhade Pune
  • Deepa Topandas Tekwani MIMER Medical College Talegaon Dabhade Pune
Keywords: polypoid lesions, nasal cavity, paranasal sinuses, nasopharynx


Background: The parts of the upper respiratory tract included in the present study are- Nasal Cavity, Paranasal sinuses and Nasopharynx. Majority of the lesions at these sites are polypoid. It is difficult to comment upon the nature of the lesion- whether neoplastic or non-neoplastic. Hence histopathological examination is essential for both ENT surgeons as well as pathologists.Methods: The study involved an analysis of specimens received in the surgical pathology laboratory from the department of ENT over a period 5 years.Result: A study of 104 lesions was undertaken. They constituted 3.06% of the total histopathological work load at our institution. Inflammatory and tumor like lesions constituted 74.04% followed by malignant tumors constituting 13.46% and benign tumors constituting 12.50% of the total number of cases.Conclusion: The age group in this study ranged from 7 to 75 years. Inflammatory and tumor like lesions were seen in all age groups, while benign tumors showed a peak incidence in the 1st and 2nd decade and  malignat lesions were common in the 4th to 6th decade. Males were more commonly affected by the various lesions as compared to females. Inflammatory and tumor like lesions were the most common lesions occurring at these sites, followed by malignant tumors and benign tumors respectively

Author Biographies

Janice Jaison, MIMER Medical College, Talegaon Dabhade Pune
Assistant ProfessorDept. of Pathology
Deepa Topandas Tekwani, MIMER Medical College Talegaon Dabhade Pune
Department of PathologyAssociate Professor


1. Ash J. E., Beck M. R., Wilkes J. D., Tumors of the upper respiratory tract and ear in Atlas of Tumor Pathology, 1964; Section IV, Fascicles 12,13 Armed Forces Institute of Pathology, Washington D.C.
2. Buchnan G and Salvin G, Tumors of nose and paranasal sinuses. A clinicopathological study. Journal Laryngol Otology1972; 86:685
3. Ghosh A and Bhattacharya K., The nasal and nasopharyngeal growths. A 10 years study. Journal Indian Med. Assoc. 1966; 47:14
4. Tondon P. L., Gulati J. and Mehta N., Histopathological study of polypoidal lesions in the nasal cavity. Indian Journal of Otolaryngol, 1971; 13:3
5. Friedman I & Osborn D. A., Pathology of Granulomas and Neoplasms of the Nose and Paranasal Sinuses. Churchill Livingstone, Edinburgh London Melbourne and New York 1982
6. Kakar P., Sinha A., The problems of scleroma in India. Indian Journal toof Olaryngol, 1964; 16:164
7. C Ratnakar, M Madhavan, Vanaja Sankaran, Andrew J Veliath, N K Majumdaar, Vasudev Anand Rao. Rhinosporidiosis in Pondicherry. Journal of Tropical Medicine and Hygiene, 1992; 95 (4):280-283.
8. J. H. Makannavar, S. Sateesh Chavan: Rhinosporidiosis- A clinicopathological study of 34 cases. Indian J Pathol Microbiol 2001; 44(1):17-21
9. Ahluwalia H. K. B., New interpretation of Rhinosporidiosis. J Submicrosc Cytol Pathol. 1992; 24: 109-11
10 .Anand C. S., Agarwal S. R.: A histopathological study in Atrophic Rhinitis. JIMA, 1972; 59:278-281
11. Sinha S. N., Samuel K.C., Juneja HIS, Mittal D.P: A study of exfoliative cytology of atrophic rhinitis. J Laryngol Otol, 1975; 89:1027-1041
12. Ishwar Singh, R. M. Raizada, V. N. Chaturvedi, S. K. T. Jain, S.N. Ingole Study of histopathological changes in Atrophic Rhinitis, Indian Journal of Otolaryngology and Head & Neck Surgery, 1999; Vol 51, No.1: 21-24
13. English GM, Hemenway WG, Cundy RL: Surgical treatment of angiofibroma. Arch Otolaryngol, 1972; 96 (4):312
14. Biller HF, Session OG, Ogura JH: Angiofibroma- A treatment approach. Laryngoscope, 84; 695-705
15.Lawson W, Billen H. F., Jacobson A, Som P, The role of conservative surgery in the management of inverted papilloma. Laryngoscoy, 1983 (2); 93:148-155.
16 .Frazell EL, Lewis JJ: Cancer of nasal cavity and accessory sinuses. Report of management of 416 patients. Caner, 1963; 16:1263
17. Acheson E. D., Cowdell R. H., Jolles B., Nasal cancer in the Northampshire Boot and Shoe Industry. Br. Med. Journal 1970; 1: 385-93
18 .Lewis J. S., Castro E. B., Cancer of the nasal cavity and paranasal sinuses. J Laryngol Otol, 1972; 86: 255-262
19. Cheng VST, Wang CC: Carcinoma of the paranasal sinuses. A study of 66 casees. Cancer, 1977; 40 (6):3038-3041
Original Article