Squamous Cell Carcinoma Vulva in a Young Woman
Keywords:
vulvar cancer, squamous cell carcinoma, pap smear, vulvar biopsy.
Abstract
Carcinoma of vulva is an uncommon malignancy accounting for only 2% of all female genital malignancies. It is usually seen in postmenopausal women in age group ≥65 yrs. Increased life expectancy has given place to carcinoma vulva among gynaecological malignancies. However in recent years there is an increased incidence (almost doubled) of vulvar cancer in younger women. We report a case of invasive squamous cell carcinoma of vulva stage IIIb in a 36 year old woman, indeed first only in thirty years of gynaecological practical experience. The relative rarity of vulvar cancer in young age and the general lack of awareness of typical signs and symptoms even by medical professionals frequently lead to a delay in diagnosis.References
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13.van Doorn HC, Ansink A, Verhaar-Langereis MMJ, et al.Neoadjuvant chemoradiation for advanced primary vulvar cancer. Cochrane Database Syst Rev 2006, Issue 3. Art. No.: CD003752. DOI:10.1002/14651858.CD003752.pub2
14.www.cancerresearchuk.org/.../a-study-looking-at-testing-sentinel-lymph-nodes-radiotherapy-and-chemotherapy-for-vulval-cancer.
2.Cancer Research UK. UK vulva cancer incidence statistics, 2008 (http://info.cancerresearchuk.org/cancerstats/types/vulva/incidence/?a=5441; accessed 20 August 2009) 15.
3. Julia E, Palmer and Alan M Gillespie Diagnosis and management of squamous cell vulvar carcinoma. Trends in urology, gynaecology and sexual health. March- April 2010;20-5
4. Toki T, Kurman RJ, Park JS, Kessis T, Daniel RW, Shak KV. Probable nonpapillomavirus etiology of squamous cell carcinoma of the vulva in older women:a clinicopathologic study using in situ hybridization and polymerase chain reaction.Int J Gynecol Pathol. 1991;10:107–125
5. Pecorelli S. Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium. Int J Gynecol Obstet 2009;105:103–4.
6. Royal College of Obstetricians and Gynaecologists. Management of vulval cancer. London: RCOG Press, 2006
7.Madsen BS, Jensen HL, van den Brule AJ, et al. Risk factors for invasive squamous cell carcinoma of the vulva and vagina--population-based case-control study in Denmark. Int J Cancer 2008; 122:2827.
8.de Koning MN, Quint WG, Pirog EC. Prevalence of mucosal and cutaneous human papillomaviruses in different histologic subtypes of vulvar carcinoma. Mod Pathol 2008; 21:334.
9. Edgren G, Sparen P. Risk of anogenital cancer after diagnosis of cervical intraepithelial neoplasia: a prospective population-based study. Lancet Oncol 2007;8:311–6.
10. Kalliala I, Anttila A, Pukkala E, et al.Risk of cervical and other cancers after treatment of cervical intraepithelial neoplasia: retrospective cohort study BMJ2005;331:1183–5.
11. Selman TJ, Luesley DM, Acheson N, et al. A systematic review of the accuracy of diagnostic tests for inguinal lymph node status in vulvar cancer. Gynecol Oncol2005;99:206–14.
12. Royal College of Pathologists. Dataset for histological reporting of vulval neoplasms,version 2, 2nd edn. London: Royal College of Pathologists, 2008.
13.van Doorn HC, Ansink A, Verhaar-Langereis MMJ, et al.Neoadjuvant chemoradiation for advanced primary vulvar cancer. Cochrane Database Syst Rev 2006, Issue 3. Art. No.: CD003752. DOI:10.1002/14651858.CD003752.pub2
14.www.cancerresearchuk.org/.../a-study-looking-at-testing-sentinel-lymph-nodes-radiotherapy-and-chemotherapy-for-vulval-cancer.
Published
2016-10-04
Issue
Section
Case Reports
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