Syphilis in Blood Donors in Tertiary Care Teaching Hospital

  • Ravi Jain Dept. of Pathology MGM Medical College Indore
  • Ashok Yadav Associate professor Department of Pathology MGM Medical College Indore
Keywords: Treponema pallidum, Seroprevalence, Transfusion transmitted diseases, Voluntary donors, Replacement donors


 Introduction -Transmission of infectious diseases through donated blood is of concern to blood safety as transfusion forms an integral part of medical and surgical therapy. Blood transfusion carries the risk of transfusion-transmissible infections, including HIV, hepatitis, syphilis, malaria and infrequently toxoplasmosis.Aims & Objectives -To find out the seroprevalence of Syphilis in blood donors, to find the incidence of spectrum of Transfusion transmitted dieasess in blood bank donation &  to find the age distribution of the cases studied.Material & methods -The present study was undertaken in the Department of Pathology MGM Medical College Indore. This is a retrospective study that was conducted, during the period 2008 –2015. The screening for Syphilis  was done by rapid chromatographic assay for detection of antibodies to T.pallidum Results - Out of total 137689 blood donations, majority of donors are voluntary donors 83.02 % as compared to replacement donors 17.05 %. Seroprevalence of Anti TP  is 0.26 %.  Seroprevalence  of Anti TP  is higher in the age group 26-35 year . Among Voluntary & replacement/relative donors . Overall seropositivity of TTI’s (HIV,HBV,HCV,Syphilis & Malaria)  is higher in replacement donors  3.71 % as compared to voluntary donors 1.75 %.Conclusion -voluntary blood donation should be encouraged for prevention of transfusion-transmissible diseases. The time and cost involved in screening donated blood can be reduced by an effective donor education and selection program that promotes self-exclusion by donors at risk of transfusion-transmissible infections.   DOI: 10.21276/AABS.1687

Author Biographies

Ravi Jain, Dept. of Pathology MGM Medical College Indore
Assistant ProfessorDept. of PathologyMGM Medical CollegeIndore
Ashok Yadav, Associate professor Department of Pathology MGM Medical College Indore
Associate professorDepartment of PathologyMGM Medical CollegeIndore


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