Transfusion Transmitted Diseases Among Blood Donors In Tertiary Care Teaching Hospital Of Central India

  • Ravi Jain Dept. of Pathology MGM Medical College Indore
  • Ashok Yadav Dept of Pathology MGM Medical College Indore
Keywords: Hepatitis B, Hepatitis C, Transfusion transmitted diseases, Voluntary donors, Syphilis, Replacement donors


Introduction -Transmission of infectious diseases through donated blood is of concern to blood safety as transfusion forms an integral part of medical and surgical therapy. Among all infections HIV and hepatitis are the most dreadful.Aims & Objectives -To find out the Seroprevalence of transfusion-transmissible infections in blood donors, to find the incidence of spectrum of diseases in blood bank donation, to find the age distribution of the cases studied.Methods -The present study is being undertaken in the Department of Pathology MGM Medical College Indore. This is a retrospective study that was conducted, during the period 2001 –2016. Tests are routinely done on every blood unit to exclude HIV, HBV, HCV, syphilis and malaria. The screening for HIV was done by ELISA using kits. HBS Ag was detected by ELISA. Anti-HCV test was done by ELISA& Syphilis by VDRL.Results - In the present study, 241571 blood donors were observed in the year 2001-16, majority of donors are voluntary donors 68.13 % as compared to replacement/relative donors 31.86 %. Majority of donors are male donors 96.25 % as compared to female donors 3.74%.Seroprevalence of HBV,HCV, HIV& SYPHILIS are 1.80 %, 0.098%, 0.20% and 0.26 % respectively. Seroprevalence is higher in the age group 26-35 years. Overall seropositivity of TTI’s (HIV,HBV, HCV, Syphilis & Malaria) is higher in replacement donors 3.12 % as compared to voluntary donors2.01 %. Over all Seroprevalence of transfusion transmitted disease in all donations in the year 2001-16 is 2.36 %.Conclusion -Voluntary blood donation should be encouraged for prevention of transfusion-transmissible diseases. 

Author Biographies

Ravi Jain, Dept. of Pathology MGM Medical College Indore
Assistant ProfessorDept. of PathologyMGM Medical CollegeIndore
Ashok Yadav, Dept of Pathology MGM Medical College Indore
Associate ProfessorDept of PathologyMGM Medical CollegeIndore


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Original Article