Evaluation of activities of pathological anatomy laboratory in a developing countriy: experience of the University Teaching Hospital of Lomé, Togo.

  • Tchin DARRE Department of Pathology of the University Teaching Hospital of Lomé, Togo. University of Lomé, Togo
  • Yaovi Edem James Department of Anatomy of the University Teaching Hospital of Lomé, Togo
  • Mohamed Kouyaté Department of Pathology of the University Teaching Hospital of Cocody, Ivory Coast
  • Alphonse Aman N'Guessen Department of Pathology of the University Teaching Hospital of Cocody, Ivory Coast
  • Koffi Amégbor Department of Pathology of the University Teaching Hospital of Lomé, Togo
  • Gado Napo-Koura
Keywords: Laboratory of pathology, developing countries, feedback activities, Togo.


BackgroundThe Laboratory of Pathology (LAP) of the Tokoin teaching hospital of Lomé, like most pathology laboratories in developing countries, experiences many problems. The aim of this study was to identify problems that under the optimal functioning of the laboratory, to propose solutions to improve the performance of this structure.MethodsA retrospective study of sample results which were analyzed inthe pathology laboratory of the Tokoin Teaching Hospital of Lomé on 5 years (2010-2014) was performed, followed by a field observation and a staff survey.ResultsIt appears that the LAP must be equipped in equipment and reagents, and technical organization and implement a self-assessment program and equipment maintenance must be improved. The LAP also experienced lack of qualified personnel. The most frequently diagnosed disease were benign mastopathies (15.8%) followed by leiomyomas (14.2%) and gastritis (9.3%).ConclusionDespite the limitations of our study, it had the merit of highlighting problems at every level of challenging work system.  The medical staff and other administrative authorities are indexed for a better service delivery to patients.


1. Cooper K and Fitzgibbons PL. Institutional consultations in surgical pathology: how shoulds diagnostic Disagreements be Handled? Arch Pathol Lab Med 2002; 126: 650-1.

2. Rauch CA, JH Nichols. Laboratory accreditation and inspection. Clin Lab Med. 2007; 27 (4): 845-58.

3. Arbiser ZK, Folpe AL, Weiss SW. Consultative (expert) second opinions in soft tissue pathology. Analysis of problem-prone diagnostic situations. Am J Clin Pathol. 2001; 116 (4): 473-6.

4. World Health Organization. Biosafety manual laboratory, Geneva, WHO 3rd ed. 2005.

5. St. Andrew JP, Donzel JP, Anger E, Chatele Ft, Cochand Priollet-B, de Graeve P, et al.
[Practice guidelines in Pathologic Anatomy and Cytology. Document Prepared by the French Association of Quality Assurance in Pathologic Anatomy and Cytology (AFAQAP). Commission No. 4: organization and functioning of Pathological Anatomy and Cytology]. Ann Pathol. 1998; 18 (3): 227-36.

6. Buesa RJ. Histology without formalin? Ann Diagn Pathol. 2008; 12 (6): 387-96.

7. Moelans CB, ter Hoeve N, JW van Ginkel, ten Kate FJ, van Diest PJ. Formaldehyde substitute fixative. Analysis of macroscopy, morphologic analysis, and immunohistochemical analysis. Am J Clin Pathol. 2011; 136 (4): 548-56.

8. Wetherington RW, Cooper RW, Al-Saleem T, DS Ackerman, R McDonnell-Adams, Davis W, et al. Clinical significance of performing immunohistochemistry were boxes with a previous diagnosis of cancer coming to a national comprehensive cancer center for treatment or second opinion. Am J Surg Pathol. 2002; 26 (9): 1222-30.

9. International Organization for Standardization (2003) Laboratory medical analyzes: Particular requirements for quality and competence. EN-ISO 15189: 2003 (E), Brussels.

10. Raymaekers M, Bakkus M, Boone E, de Rijke B, El Housni H, Reflections and proposals to assure quality in molecular diagnostics. Acta Clin Belg. 2011;66(1):33-41.

11. MS-ASPFPE (2002) performance of Togo biology analyzes Guide. Lomé, 22 p.

12. Katawa G, Kpotsra A, Karou DS, M Eklou, Tayi KE, de Souza C. [Contribution to the establishment of quality assurance in medical microbiology five departments in Togo]. Bull Soc Pathol Exot. 2011; 104 (1): 20-4.
Original Article