Cytodiagnosis of Chondrosarcoma: A case report
Keywords:
FNAC, Chondrosarcoma, chest wall
Abstract
Primary tumors involving the bony skeleton of the chest wall are uncommon. Chondrosarcomas of thorax are unusual tumors categorized as axial malignancies that invade and destroy the adjacent bone. Fine needle aspiration cytology (FNAC) is effective in the diagnosis of bone tumors when combined with careful radiologic and clinical evaluation. Chondrosarcomas often arise in the pelvis or bones of the trunk, but primary chest wall (rib) chondrosarcomas are relatively rare. Incidence of chondrosarcoma peaks in the 5th to 6th decade. We present a two cases one of 58-year-old male with anterior chest wall mass and another of 70-year-old male presented with anterolateral chest wall mass. Fine needle aspiration was done and smear studied showed increased cellularity with chondromyxoid background and tissue fragment with chondrocytes showing anisonucleosis and nuclear pleomorphism. Few binucleate cells were seen and few nuclei showed prominent nucleoli. The diagnosis of chondrosarcoma was considered.References
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2. Karam B M, Zahirifard S, Kaynama K, Ehsanpour A, Masjedi M . Chondrosarcoma Arising in the Posterior Part of a Rib with Dumb-Bell Shaped Extension to the Adjacent Intervertebral Foramen; A Rare and Unusual Presentation. Iran.J. Radiol., 2004;2(1):21-24.
3. Singhal A, Mahajan C, Hadi R, Awasthi NP. Chondrosarcoma of chest wall metastasising to the larynx: Case report and review of literature. J Can Res Ther 2015;11:658.
4. Mukherjee K, Pal M, Saha M, Maity N, Halder S Ghosh R. Giant Chondrosarcoma of Chest Wall. Indian J Chest Dis Allied Sci 2013;55:229-231.
5. Orell SR, Sterrett GF, Whitaker D. Fine Needle Aspiration Cytology 4th edition. Churchill Livingstone Elsevier 2005.
6.Bibbo M, Wilbur DC. Comprehensive Cytopathology 3rd edition. Sounders Elsevier 2008.
7. Rosai J. Rosai and Ackerman’s Surgical Pathology,Bone tumours. 10th ed. NewYork: Mosby Elsevier; 2011.
8. Dorfman HD, Czerniak B. Chondrosarcoma In: bone tumors St Lovis, Mosby 1998:395-410.
9. Czerniak B ,Tuziak T , Kram A, Ayala A.Bone tumors In: Koss, Leopold G, Myron R. Koss' Diagnostic Cytology and Its Histopathologic Bases, 5th Edition. Lippincott Williams and atkins .
10. Tunç M, Ekinci C. Chondrosarcoma diagnosed by fine needle aspiration cytology. Acta Cytol, 1996;40:283-8.
11 . MitraB, Choudhury A R, Bhattacharya P, Paul B. Rare Occurrence of Primary Chest Wall Bone Tumors. Open Journal of Orthopedics. 2012;2:138-143.
Published
2015-12-11
Issue
Section
Case Reports
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