Histomorphological spectrum of Ovarian tumors in a tertiary care hospital
Keywords:
Ovarian tumors, histology, surface epithelial tumors, benign, borderline, malignant
Abstract
Background: To study or analyse the histomorphological spectrum and distribution of benign and malignant ovarian neoplasms in women of different age groupsMethods: 633 cases of ovarian tumors were studied over a period of 6 years(from July 2011 to July 2017) at the Department of Pathology, SDMH. All the cases were subjected to histopathological examination and IHC as & when required.Results: In total,633 ovarian tumor specimens were examined. Out of which ,468 cases (73.9%)were benign, 23 (3.6%)were boderline and 142(22.4%)were malignant. Most of the benign tumors occurred between 31 & 40 years of age while malignant lesions presented commonly between 41 & 50 years of age. Most common histological types were serous cystadenoma (24.18%) followed by mature cystic teratoma (22.90%).The commonest benign tumor was serous cystadenoma & the commonest malignant tumor was serous cystadenocarcinoma. Serous tumors showed bilateral involvement more commonly than bilateral mucinous tumors.Conclusion-: We noted that serous cystadenoma tumors are the commonest variety of ovarian tumors. Also the age of presentation of these malignant tumors was an earlier age as compared to others. DOI: 10.21276/AWCH.1804References
1. Agrawal P, Kulkarni DG, Chakrabarti PR , Chourasia Sapna, Dixit Monal,et al. Clinicopathological Spectrum of Ovarian Tumors: A 5‑Year Experience in a Tertiary Health Care Center. Journal of Basic and Clinical Reproductive Sciences 2015 . July 4 (2) :90-6
2. Tortolero-Luna G, Mitchell MF. The epidemiology of ovarian cancer. J Cell Biochem Suppl 1995;23:200-7
3. Mondal SK, Banyopadhyay R, Nag DR, Roychowdhury S, Mondal PK, Sinha SK. Histologic pattern, bilaterality and clinical evaluation of 957 ovarian neoplasms: A 10-year study in a tertiary hospital of eastern India. J Can Res Ther 2011;7:433-7.
4. Consolidated Report of Population Based Cancer Registries 2001-2004. National Cancer Registry Program Indian Council of Medical Research. Bangalore, 2006.
5. Nishal AJ ,Naik KS, Modi Jigna. Int J Res Med Sci. 2015 Oct;3(10):2714-2717
6. Murthy NS, Shalini S, Suman G, Pruthvish S, Mathew A. Changing trends in incidence of ovarian cancer - the Indian scenario. Asian Pac J Cancer Prev 2009;10:1025-30
7. Tortolero L, Mictchell FM, Rhodes HE. Epidemiology and screening of ovarian cancer.
Obstet Gynecol Clin North Am. 1994;21:63-75.
8. Sheikh S , Humaira Bashir, Summyia Farooq,Arshi Beigh, Farzana Manzoor, et al. Int J Res Med Sci. 2017 May;5(5):2110-2114
9. Saxena MHK, Devi G, Prakash P, Pantrajan P. Ovarian neoplasms-A retrospective study of 356 cases. J Obstret Fynec India. 1980;30:522-7
10. Gupta N, Bisht D, Agarwal AK, Sharma VK. Retrospective and prospective study of ovarian tumours and tumour like lesions. Indian J Pathol Microbiol. 2007;50:525-7.
11. Gupta GC, Singh PA, Mehrotra TN, Agarwal R: A clinicopathological study of ovarian tumours. Indian J Pathol Microbiol. 1986;29:354-62
12. Maheshwari V, Tyagi SP, Saxena K, Tyagi N, Sharma R, Aziz M, Hameed F. Surface epithelial tumours of the ovary. Indian J Pathol Microbiol. 1994;37:75-85.
13. Ahmad Z, Kayani N, Hasan S, Muzaffar S, Gill M. Histopathological pattern of ovarian neoplasms. J Pak Med Assoc. 2000;50(12):416-9.
14. Pilli G S, Suneeta KP, Dhaded A V, Yenni VV. Ovarian tumours: a study of 282 cases: J Indian Med Assoc. 2002;100:420:423-4.
15. Malik IA. A Prospective Study of Clinicopathological Features of Epitheliall Ovarian Cancer in Pakistan. J Pak Med Assoc. 2002;52(4):155-8.
16. Yasmin S, Yasmin A, Asif M. Clinicohistological pattern of ovarian tumors in Peshawar region. J Ayub Med Coll Abbottabad 2008; 20(4):11–3.
17. Pachori G, Meena US, Sunaria RK, Pachori P, Jethani N, Bayla T et al. Histopathological study of ovarian tumors in Ajmer region. Int J Med Sci Public Health 2016;5: 1400-03
18. Kushima Miki.Problems in the pathological diagnosis and Intraoperative rapid diagnosis of mucinous tumor of the ovary.Showa Uni Med Sci 2013 ;25(1):1-7
19. Lee KR, Tavassoli FA, Prat J, et al. Surface epithelia-stromal tumors. In Tavassolt FA, Devtlee P, eds. Pathology and genetics of tumors of the breast and female genital organs. Lyon: IARC Press, 2003. Pp117-145. (World health organization classification of tumors; 4)
20. Zaman S, Majid S, Hussain M, Chughtai O, Mahboob J, Chughtai S. A retrospective study of ovarian tumours and tumour-like lesions. J Ayub Med Coll Abbottabad 2010;22(1):104–8
21. Murthy NS, Shalini S, Suman G, Pruthvish S, Mathew A. Changing trends in incidence of ovarian cancer- the Indian scenario. Asian Pac J cancer prev. 2009;10(6):1025-30
22. Kanthikar SN, Dravid NV, Deore PN, Nikumbh DB, Suryawanshi KH. Clinico-histopathological analysis of neoplastic and non- neoplastic lesions of the ovary: a 3-year prospective study in Dhule, North Maharashtra, India. J Clin Diagn Res 2014;8(8): 4–7.
2. Tortolero-Luna G, Mitchell MF. The epidemiology of ovarian cancer. J Cell Biochem Suppl 1995;23:200-7
3. Mondal SK, Banyopadhyay R, Nag DR, Roychowdhury S, Mondal PK, Sinha SK. Histologic pattern, bilaterality and clinical evaluation of 957 ovarian neoplasms: A 10-year study in a tertiary hospital of eastern India. J Can Res Ther 2011;7:433-7.
4. Consolidated Report of Population Based Cancer Registries 2001-2004. National Cancer Registry Program Indian Council of Medical Research. Bangalore, 2006.
5. Nishal AJ ,Naik KS, Modi Jigna. Int J Res Med Sci. 2015 Oct;3(10):2714-2717
6. Murthy NS, Shalini S, Suman G, Pruthvish S, Mathew A. Changing trends in incidence of ovarian cancer - the Indian scenario. Asian Pac J Cancer Prev 2009;10:1025-30
7. Tortolero L, Mictchell FM, Rhodes HE. Epidemiology and screening of ovarian cancer.
Obstet Gynecol Clin North Am. 1994;21:63-75.
8. Sheikh S , Humaira Bashir, Summyia Farooq,Arshi Beigh, Farzana Manzoor, et al. Int J Res Med Sci. 2017 May;5(5):2110-2114
9. Saxena MHK, Devi G, Prakash P, Pantrajan P. Ovarian neoplasms-A retrospective study of 356 cases. J Obstret Fynec India. 1980;30:522-7
10. Gupta N, Bisht D, Agarwal AK, Sharma VK. Retrospective and prospective study of ovarian tumours and tumour like lesions. Indian J Pathol Microbiol. 2007;50:525-7.
11. Gupta GC, Singh PA, Mehrotra TN, Agarwal R: A clinicopathological study of ovarian tumours. Indian J Pathol Microbiol. 1986;29:354-62
12. Maheshwari V, Tyagi SP, Saxena K, Tyagi N, Sharma R, Aziz M, Hameed F. Surface epithelial tumours of the ovary. Indian J Pathol Microbiol. 1994;37:75-85.
13. Ahmad Z, Kayani N, Hasan S, Muzaffar S, Gill M. Histopathological pattern of ovarian neoplasms. J Pak Med Assoc. 2000;50(12):416-9.
14. Pilli G S, Suneeta KP, Dhaded A V, Yenni VV. Ovarian tumours: a study of 282 cases: J Indian Med Assoc. 2002;100:420:423-4.
15. Malik IA. A Prospective Study of Clinicopathological Features of Epitheliall Ovarian Cancer in Pakistan. J Pak Med Assoc. 2002;52(4):155-8.
16. Yasmin S, Yasmin A, Asif M. Clinicohistological pattern of ovarian tumors in Peshawar region. J Ayub Med Coll Abbottabad 2008; 20(4):11–3.
17. Pachori G, Meena US, Sunaria RK, Pachori P, Jethani N, Bayla T et al. Histopathological study of ovarian tumors in Ajmer region. Int J Med Sci Public Health 2016;5: 1400-03
18. Kushima Miki.Problems in the pathological diagnosis and Intraoperative rapid diagnosis of mucinous tumor of the ovary.Showa Uni Med Sci 2013 ;25(1):1-7
19. Lee KR, Tavassoli FA, Prat J, et al. Surface epithelia-stromal tumors. In Tavassolt FA, Devtlee P, eds. Pathology and genetics of tumors of the breast and female genital organs. Lyon: IARC Press, 2003. Pp117-145. (World health organization classification of tumors; 4)
20. Zaman S, Majid S, Hussain M, Chughtai O, Mahboob J, Chughtai S. A retrospective study of ovarian tumours and tumour-like lesions. J Ayub Med Coll Abbottabad 2010;22(1):104–8
21. Murthy NS, Shalini S, Suman G, Pruthvish S, Mathew A. Changing trends in incidence of ovarian cancer- the Indian scenario. Asian Pac J cancer prev. 2009;10(6):1025-30
22. Kanthikar SN, Dravid NV, Deore PN, Nikumbh DB, Suryawanshi KH. Clinico-histopathological analysis of neoplastic and non- neoplastic lesions of the ovary: a 3-year prospective study in Dhule, North Maharashtra, India. J Clin Diagn Res 2014;8(8): 4–7.
Published
2017-12-15
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