Castleman Disease- An Uncommon And Intriguing Condition Revisited: A Report Of Two Cases

Shubhangi Vinayak Agale, Sushama N. Ramraje, Sameer Ansari, Pinkesh Gugaliya, Banasri Devi, Grace F. D’Costa

Abstract


Castleman disease (CD) also called as angiofollicular hyperplasia or giant lymph node hyperplasia of unknown cause is a benign lymphoproliferative disorder. It is a localised (unicentric) or disseminated (multicentric) disease. This disease is uncommon with an incidence of 25 cases per million person per year. Castleman disease is a heterogeneous group of disorders with four characteristic histological variants. The etiology of this disease is poorly understood.
We report two cases of CD, one presenting with a neck mass and the other presenting with para-aortic and mesenteric lymphadenopathy which were classified as hyaline vascular type and mixed type of CD respectively.

DOI: 10.21276/APALM.1559


Keywords


Lymph node, Castleman disease, Hyaline vascular, Mixed variant

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References


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