Is Cytology Safest Modality Available in Armamentarium for Diagnosis of Hodgkin’s Lymphoma in Pregnancy?
Keywords:
Fine needle aspiration, Cytology, Lymph node, Lymphoma.
Abstract
Hodgkin’s lymphoma (HL) is one of the curable diseases in pregnancy. Since pregnant females are immuno-compromised, so it is important to know about the course and progression of this common entity in pregnancy. Fine needle aspiration cytology is minimally invasive and a safe approach to diagnose and subtype such cases as early diagnosis and effective treatment will lead to better outcome of the mother and fetus. Here we present a case of nodular sclerosis Hodgkin’s lymphoma in a pregnant female diagnosed on cytology with histopathological confirmation and immuno-histochemical analysis.References
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by Hodgkin’s disease. Med J Malaysia. 2006;61(3):358-360.
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Eur J Cancer. 2006;42(2):126-140.
2) Bachanova V, Connors JM. Hodgkin lymphoma in pregnancy. Curr Hematol Malig Rep. 2013 Sep;8(3):211-7.
3) Kassab C, Fleury G, Weinschenker P, Rodrigues F, Hamerschlak N. Hodgkin’s disease and pregnancy: case series and proposal for treatment protocol. Einstein. 2011;9:216-219.
4) Harris NL, Jaffe ES, Diebold J, et al. The World Health Organization classification of neoplastic diseases of the haematopoietic and lymphoid tissues: report of the Clinical Advisory Committee Meeting, Airlie House, Virginia, November 1997. Histopathology 2000;36:69–87.
5) Sanchez M, Pellicer B, Cozar MP, Martínez-Sanjuan V, Villegas C, Carbonell F. Hodgkin Lymphoma in Pregnancy. Clinical Advances in Hematology & Oncology2013; (11):533-36.
6) Mason DY, Banks PM, Chan J, et al. Nodular lymphocyte predominance Hodgkin’s disease: a distinct clinicopathologic entity. Am J Surg Pathol 1994;18:526–30.
7) Falini B, Pileri S, Stein H, et al. Variable expression of leukocyte common antigen (CD45) in CD30 (Ki-1)-positive anaplastic large cell (ALC) lymphoma. Implication for the differential diagnosis between lymphoid and non-lymphoid malignancies. Hum Pathol 1990;21:624–9.
8) Pileri SA, Ascani S, Leoncini L, Sabattini E, Zinzani P L, Piccaluga P P, et al. Hodgkin’s lymphoma: the pathologist’s viewpoint J Clin Pathol 2002;55:162–176.
9) Fadilah SA, Leong CF, Jamil MY, Cheong SK, Rozilaila R. Pregnancy complicated
by Hodgkin’s disease. Med J Malaysia. 2006;61(3):358-360.
10) Eyre TA, Lau IJ, Mackillop L, Collins GP. Management and controversies of classical Hodgkin lymphoma in pregnancy. Br J Haematol. 2015 Jun;169(5):613-30.
Published
2018-07-16
Issue
Section
Case Report
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