A Study of Spectrum of Adipose Tissue Tumours At A Tertiary Care Hospital, Gujarat
Keywords:
Adipose tissue tumors (ATT), Benign ATT, Malignant ATT, Lipoma.
Abstract
INTRODUCTION: Adipose Tissue Tumors(ATT) are the most common benign soft tissue tumors in humans. The actual incidence of Adipose Tissue Tumors is probably higher than reported because of its insidious slow growing pattern and minimal associated symptoms. The purpose of our study is to evaluate pattern of distribution of the adipose tissue tumours in relation to different age groups, sex and anatomical site distribution and frequency of various benign & malignant variants. MATERIAL AND METHOD: The present study has been done in Histopathology section of Pathology Department of Government Medical College & Sir T General Hospital,Bhavnagar for the period of 2 years from 01/01/2013 to 31/12/2015.Total 87 cases were studied. RESULTS: In the present study, adipose tissue tumours constitute 1.33% of total yearly histopathological specimens. The incidence of benign soft tissue tumours is 96.55% and that of malignant tumours is 3.45%. Ratio of benign to malignant ATT is 28:1. Commonest age group for benign tumors was 30-50 years & for malignant lesions above 50 yrs age. Overall incidence of adipose tissue tumors is slightly higher (52.87%) in females in comparison of males (47.13%). The most common benign variant of lipoma is fibrolipoma. CONCLUSION: Present study concludes preponderence of Benign Adipose Tissue Tumours overall and also in females with trunk being a favourable site. Malignant tumours are common in males with lower extremities being the commonest site.References
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12. Rydholm A, Berg NO. Size, site and clinical incidence of lipoma. Factors in the differential diagnosis of lipoma and sarcoma. Acta Orthop Scand. 1983;54:929-34.
13. C. Balakrishna, D. Nanavati, A. Balakrishnan, “Giant lipomas of the upper extremity: Case reports and aliterature review,” Can J Plast Surg. 2012; XX (3):40–41.
14. C. Davis, J.G. Gruhn, “Giant lipoma of the thigh,” Arch Surg. 1967;95:151-6.
15. Rosenberg AE. Bones, joints and soft-tissue tumours. In: Kumar V, Abbas A, Fausto N, editors. Robbins and Cotran Pathologic Basis of Disease. 8th ed. Philadelphia, PA. USA: Saunders Elsevier;2010:1249-50.
16. Enzinger FM, Winslow DJ. Liposarcoma. A study of 103 cases. Virchows Arch Pathol Anat Physiol Klin Med 1962;335:367-88.
17. Antonescu C, Ladanyi M. Myxoid liposarcoma In: Fletcher CD, Unni KK, Mertens F, editors. World Health Organization Classification of Tumours: Pathology and Genetics of tumours of Soft Tissue and Bone. Lyon: IARC Press;2002:40-3.
2. B Allen, C Rader, A Babigian. Giant lipomas of the upper extremity. Can J Plast Surg. 2007;15(3):141-4.
3. Terzioglu A, Tuncali D, Yuksel A, Bingul F, Aslan G. Giant lipomas: A series of 12 consecutive cases and a giant liposarcoma of the thigh. Dermatol Surg. 2004;30:463-7.
4. Cribb GL, Cool WP, Ford DJ, Mangham DC. Giant lipomatous tumours of the hand and forearm. J Hand Surg [Br]. 2005;30:509-12.
5. Celik C, Karakousis CP, Moore R, Holyoke ED. Liposarcomas: Prognosis and management. J Surg Oncol. 1980;14:245-9.
6. Silistreli OK, Durmus EU, Ulusal BG, Oztan Y, Gorgu M. What should be the treatment modality in giant cutaneous lipomas? Review of the literature and report of 4 cases. Br J Plast Surg. 2005;58:394-8.
7. Rosai J. Soft tissue tumours. In: Rosai and Ackerman’s Surgical Pathology. 10th ed., Vol. II. New York, NY, USA; Mosby an Imprint of Elsevier; 2011. 2140-5.
8. Weiss SW, Goldblum JR. Benign lipomatous tumours. In: Enzinger FM,Weiss SW, editors. Soft Tissue Tumours. 4th ed. Boston: Churchill Livingstone; 2001. 571-694.
9. G. Nigri, M. Dente, S. Valabrega, “Giant inframuscular lipoma disclosed 14 years after a blunt trauma: A case report,” Journal of Medical Case Reports. 2008;2:318.
10. Seleye-Fubara D, Etebu EN. Adipose tissue tumour in Port Harcourt: A ten year review. Sahel Med J. 2005;8:92-4.
11. Leffert RD. Lipomas of the upper extremity. J Bone Joint Surg Am. 1972;54:1262-6.
12. Rydholm A, Berg NO. Size, site and clinical incidence of lipoma. Factors in the differential diagnosis of lipoma and sarcoma. Acta Orthop Scand. 1983;54:929-34.
13. C. Balakrishna, D. Nanavati, A. Balakrishnan, “Giant lipomas of the upper extremity: Case reports and aliterature review,” Can J Plast Surg. 2012; XX (3):40–41.
14. C. Davis, J.G. Gruhn, “Giant lipoma of the thigh,” Arch Surg. 1967;95:151-6.
15. Rosenberg AE. Bones, joints and soft-tissue tumours. In: Kumar V, Abbas A, Fausto N, editors. Robbins and Cotran Pathologic Basis of Disease. 8th ed. Philadelphia, PA. USA: Saunders Elsevier;2010:1249-50.
16. Enzinger FM, Winslow DJ. Liposarcoma. A study of 103 cases. Virchows Arch Pathol Anat Physiol Klin Med 1962;335:367-88.
17. Antonescu C, Ladanyi M. Myxoid liposarcoma In: Fletcher CD, Unni KK, Mertens F, editors. World Health Organization Classification of Tumours: Pathology and Genetics of tumours of Soft Tissue and Bone. Lyon: IARC Press;2002:40-3.
Published
2018-07-20
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