Celiac Disease: Comparison of Oberhuber Classification and Corazza- Villanacci Classification
Keywords:
Celiac Disease, Oberhuber classification, Corazza-Villanacci classification
Abstract
Background: Celiac disease occurs in genetically predisposed individuals on consumption of certain grains. The diagnosis is based on biopsy showing the presence of characteristic histological changes in duodenum and jejunum that improve after gluten free diet. The Oberhuber Classification is very widely used by pathologists. The new Corazza-Villanacci Classification simplifies the criteria. Methods: Retrospectively diagnosed 200 patients of Celiac disease according to Oberhuber classification over duration of 05 years were considered. The 200 cases were retrieved from the records and were sent to two pathologists, who were blinded to each other and were not given any clinical information. Each pathologist received the set of biopsy specimens on two separate occasions and had reclassified them according to both grading systems in a random order. The interobserver variation was then determined after re-examination according to Oberhuber classification and after using to Corazza-Villanacci classification too Result: Mean kappa values were 0.77 (good) for the Oberhuber classification versus 0.98 (very good) for the Corazza -Villanacci classification Conclusion: The Corazza-Villanacci classification gives better interobserver agreement compared with the Oberhuber classification and contributes to the validity of diagnosis in celiac disease.References
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12. Corazza GR, Villanacci V, Zambelli C, Milione M, Luinetti O, Vindigni C, et al. Comparision of the interobserver reproducibility with different histologic criteria used in celiac disease. Clin Gastroenterol Hepatol.2007;5:838-43.
13. Gino RC, * Vincenzo V, ‡ Claudia Z, ‡ Massimo M, § Ombretta L, Carla V, ¶ et all Comparison of the Interobserver Reproducibility with Different Histologic Criteria Used in Celiac Disease clinical gastroenterology and hepatology 2007;5:838–843
14. Manas M α, Sanjay P σ, Manisha S ρ, Tejinder SB Ѡ, Mridu M ¥, Harjot K et all Celiac Disease: An Assessment of Subjective Variation and Diagnostic Reproducibility of the Various Classification Systems Global Journal of Medical Research: C Microbiology and Pathology Volume 15 Issue 1 Version 1.0 Year 2015 Type: Double Blind Peer Reviewed International Research Journal Publisher: Global Journals Inc. (USA) Online ISSN: 2249 4618 & Print ISSN: 0975-588810. Serra S, Jani PA. An approach to duodenal biopsies. J Clin Pathol.2006;59:1133-50.
2. Bao F, Green PHR, Bhagat G. An update on celiac disease histopathology and the road ahead. Arch Pathol Lab Med.2012;136:735-45.
3. Villanacci V, Ceppa P, Tavani E, Vindigni C, Volta U. Coeliac disease: The histology report. Digestive and liver disease.2011;43S:385-95.
4. Corazza GR, Villanacci V. Coeliac disease. J Clin Pathol.2005;58:573-74.
5. Oberhuber G, Granditsch G, Vogelsang H. The histopathology of celiac disease: tme for a standardized report scheme for pathologists. Eur J Gastroenterol Hepatol.1999;11:1185-94. http://dx.doi.org/10.1097/00042737-199910000-00019
6 Brenes-Pino F, Herrera A. Small Intestne Biopsy and its Interpretaton: Preliminary Results in Costa Rica. In Rodrigo L and Pena AS, editors. Celiac Disease and Non-Celiac Gluten Sensitvity. Barcelona, Spain: OmniaScience;2014.p.203-218.
7. Bao F, Bhagat G. Histopathology of celiac disease. Gastrointest Endosc Clin North Am. 2012;22:679-94.http://dx.doi.org/10.1016/j.giec.2012.07.001
8. Ensari A. Gluten-Sensitive Enteropathy (Celiac Disease): Controversies in Diagnosis and Classification. Arch Pathol Lab Med.2010;134(6):826-36
9. Drut R, Rua EC. The histopathology of pediatric celiac disease: order must prevail out of chaos. Int J Surg Path2001,9:261-264
10 Bhasin TS, Mannan R, Malhotra V, Sood N, Sood A. Bhatia PK. Hiatological recovery profiles of patients with celiac disease- An Indian perspective. J Clin Diagn Res .2010;4:2217-25.
11. Brown IS, Smith J, Rosty C. Gastrointestinal pathology in Celiac Disease: A Case series of 150 Consecutive newly diagnosed patients. Am J Clin Pathol.2012;138(1):42-9.
12. Corazza GR, Villanacci V, Zambelli C, Milione M, Luinetti O, Vindigni C, et al. Comparision of the interobserver reproducibility with different histologic criteria used in celiac disease. Clin Gastroenterol Hepatol.2007;5:838-43.
13. Gino RC, * Vincenzo V, ‡ Claudia Z, ‡ Massimo M, § Ombretta L, Carla V, ¶ et all Comparison of the Interobserver Reproducibility with Different Histologic Criteria Used in Celiac Disease clinical gastroenterology and hepatology 2007;5:838–843
14. Manas M α, Sanjay P σ, Manisha S ρ, Tejinder SB Ѡ, Mridu M ¥, Harjot K et all Celiac Disease: An Assessment of Subjective Variation and Diagnostic Reproducibility of the Various Classification Systems Global Journal of Medical Research: C Microbiology and Pathology Volume 15 Issue 1 Version 1.0 Year 2015 Type: Double Blind Peer Reviewed International Research Journal Publisher: Global Journals Inc. (USA) Online ISSN: 2249 4618 & Print ISSN: 0975-588810. Serra S, Jani PA. An approach to duodenal biopsies. J Clin Pathol.2006;59:1133-50.
Published
2019-03-17
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