Histopathological Spectrum of Oral Cavity Lesions at A Tertiary Care Hospital in South India
Keywords:
Oral lesion, Buccal mucosa, Squamous cell carcinoma
Abstract
Background: Oral cavity lesions are usually asymptomatic. Oral cancer is the most common type of cancer among males in India. Proper management of patients begins with an accurate diagnosis and histopathology is considered as the gold standard. The objective is to study the pattern of oral cavity lesions in a tertiary care hospital, Kannur, Kerala. Methods: A 1 ½ year retrospective study was carried out and included all the oral cavity specimens received in the Department of Pathology. The parameters analyzed were age, gender, site & histopathological diagnosis of the lesion. H & E slides were reviewed. Result: A total of 107 cases were studied. Age ranged from 5 years to 90 years. Males and females were equally affected (M:F = 1.05:1). Buccal mucosa was the commonest site involved. 24 cases (14 malignant,10 benign and 4 premalignant) were neoplastic and the rest were non neoplastic. Squamous cell carcinoma (11.2%) was the most common malignant lesion with favoured sites being buccal mucosa followed by tongue and tonsil. Conclusion: Good clinical examination combined with accurate histopathological study is essential to confirm the nature of the lesion.References
1) Gupta M, Choudhary H,Gupta N, Gupta A. Histopathological study of neoplastic lesions of oral cavity and oropharynx. Int J Res Med Sci. 2016 May;4(5):1506-1510
2) Agrawal R,Chouhan A,Kumar P. Spectrum of Oral Lesions in A Tertiary Care Hospital. J Clin Diagn Res. 2015 June; 9(6): EC11–EC13
3) Kosam S, Kujur P. Pattern of Oral Cavity Lesion: A Retrospective Study of 350 Cases. Int J Sci Stud 2016;4(3):65-69
4) Naderi NJ, Eshghyar N, Esfehanian H. Reactive lesions of the oral cavity: A retrospective study on 2068 cases. Dent Res J (Isfahan) 2012; 9:251-5.
5) Fierro-Garibay C, Almendros-Marqués N, Berini-Aytés L, Gay-Escoda C. Prevalence of biopsied oral lesions in a Department of Oral Surgery (2007 - 2009). J Clin Exp Dent. 2011;3(2): e73-7
6) Modi D, Laishram RS, Sharma LD, Debnath K. Pattern of oral cavity lesions in a tertiary care hospital in Manipur, India. J Med Soc 2013; 27:199-202
7) Patil PB, Bathi R, Chaudhari S. Prevalence of oral mucosal lesions in dental patients with tobacco smoking, chewing, and mixed habits: A cross-sectional study in South India. J Fam Community Med 2013; 20:130-5
8) Bhat SP, Bhat V,Permi H, Shetty JK, Aroor R, Bhandary SK. Oral and oropharyngeal malignancy: A clinicopathological study IJPLM. 2016;2(1): OA3
9) Durazzo MD, Araujo CEN, Neto JSB et al. clinical and epidemiological features of oral cancer ina medical school teaching hospital from 1994 to 2002: increasing incidence in women, predominance of advanced local disease, and low incidence of neck metastases.CLINICS 2005;60(4)293-298.
10) Mehta NV, Dave KK, Gonsai RN, Goswami HM, Patel PS, Kadam TB. Histopathological study of oral cavity lesions: A study on 100 cases. Int J Res Rev 2013; 05:110-6
11) Mehrotra R, Singh M, Kumar D, Pandey AN, Gupta RK, Sinha US. Age specific incidence rate and pathological spectrum of oral cancer in Allahabad. Indian J Med Sci 2003; 57:400-4
12) Gambhir RS, Veeresha KL, Sohi R, Kakkar H, Aggarwal A, Gupta D. The prevalence of oral mucosal lesions in the patients visiting a dental school in Northern India in relation to sex, site and distribution: A retrospective study. J Clin Exp Dent. 2011;3(1): e10-7.
13) Mirbodh SM, Ahing SI. Tobacco associated lesions of oral cavity:Part 2.Malignant lesions. J Can Dent Assoc 2000; 66:308-11.
14) Rivera C, Jones Herrera C, Vargas P, Venegas B, Drouguett . Oral diseases: A 14 year experience of a Chilean instituition with a systematic review from eight countries. Med Oral Patol Oral cir Bucal 2017 May1;22(3):297-306.
15) Satorres M, Faura M. Bresco M, Berini L, Gay Escoda C. Prevalencia de lesiones orales biopsiadas en un Servicio de Cirugía Bucal. Med Oral Patol Oral Cir Buc. 2001;6: 296-305.
16) Isaac U, Issac JS, Ahmed Khoso N. Histopathologic features of oral submucous fibrosis: A study of 35 biopsy specimens. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008; 106:556-60
2) Agrawal R,Chouhan A,Kumar P. Spectrum of Oral Lesions in A Tertiary Care Hospital. J Clin Diagn Res. 2015 June; 9(6): EC11–EC13
3) Kosam S, Kujur P. Pattern of Oral Cavity Lesion: A Retrospective Study of 350 Cases. Int J Sci Stud 2016;4(3):65-69
4) Naderi NJ, Eshghyar N, Esfehanian H. Reactive lesions of the oral cavity: A retrospective study on 2068 cases. Dent Res J (Isfahan) 2012; 9:251-5.
5) Fierro-Garibay C, Almendros-Marqués N, Berini-Aytés L, Gay-Escoda C. Prevalence of biopsied oral lesions in a Department of Oral Surgery (2007 - 2009). J Clin Exp Dent. 2011;3(2): e73-7
6) Modi D, Laishram RS, Sharma LD, Debnath K. Pattern of oral cavity lesions in a tertiary care hospital in Manipur, India. J Med Soc 2013; 27:199-202
7) Patil PB, Bathi R, Chaudhari S. Prevalence of oral mucosal lesions in dental patients with tobacco smoking, chewing, and mixed habits: A cross-sectional study in South India. J Fam Community Med 2013; 20:130-5
8) Bhat SP, Bhat V,Permi H, Shetty JK, Aroor R, Bhandary SK. Oral and oropharyngeal malignancy: A clinicopathological study IJPLM. 2016;2(1): OA3
9) Durazzo MD, Araujo CEN, Neto JSB et al. clinical and epidemiological features of oral cancer ina medical school teaching hospital from 1994 to 2002: increasing incidence in women, predominance of advanced local disease, and low incidence of neck metastases.CLINICS 2005;60(4)293-298.
10) Mehta NV, Dave KK, Gonsai RN, Goswami HM, Patel PS, Kadam TB. Histopathological study of oral cavity lesions: A study on 100 cases. Int J Res Rev 2013; 05:110-6
11) Mehrotra R, Singh M, Kumar D, Pandey AN, Gupta RK, Sinha US. Age specific incidence rate and pathological spectrum of oral cancer in Allahabad. Indian J Med Sci 2003; 57:400-4
12) Gambhir RS, Veeresha KL, Sohi R, Kakkar H, Aggarwal A, Gupta D. The prevalence of oral mucosal lesions in the patients visiting a dental school in Northern India in relation to sex, site and distribution: A retrospective study. J Clin Exp Dent. 2011;3(1): e10-7.
13) Mirbodh SM, Ahing SI. Tobacco associated lesions of oral cavity:Part 2.Malignant lesions. J Can Dent Assoc 2000; 66:308-11.
14) Rivera C, Jones Herrera C, Vargas P, Venegas B, Drouguett . Oral diseases: A 14 year experience of a Chilean instituition with a systematic review from eight countries. Med Oral Patol Oral cir Bucal 2017 May1;22(3):297-306.
15) Satorres M, Faura M. Bresco M, Berini L, Gay Escoda C. Prevalencia de lesiones orales biopsiadas en un Servicio de Cirugía Bucal. Med Oral Patol Oral Cir Buc. 2001;6: 296-305.
16) Isaac U, Issac JS, Ahmed Khoso N. Histopathologic features of oral submucous fibrosis: A study of 35 biopsy specimens. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008; 106:556-60
Published
2019-03-27
Issue
Section
Original Article
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access at http://opcit.eprints.org/oacitation-biblio.html).
