Steroid cell tumor : A rare ovarian tumor
Case Report
Keywords:
Steroid cell tumor, Ovarian tumor
Abstract
Steroid cell tumors of ovary are a rare subgroup of sex cord tumors, account less than 0.1% of all ovarian tumors and also will present at any age. Some of this tumor may be functional and secrete hormones. Nearly 56-77% of the cases present with hypergonadism. However, there may be atypical presentations of these tumors also when they do not show any symptoms of virilization. In these cases diagnosis is usually made postoperatively on finding a tumor in ovary. A careful correlation between Clinical and surgical evaluation and microscopic analysis is necessary, as is a regular follow up. We reported a case of 45 years old female with complained of abdominal pain on & off since two years. She had no other complains. Histopathology confirmed the diagnosis of steroid cell tumor not otherwise specified type (NOS type) with no cytological atypia.References
1. R. H. Young, P B. Clement, and R. E. Scully, “Sex-cord stromal, steroid cell and germ cell tumours of the ovary”, in Sternberg’s Diagnostic Surgical Pathology, S. E. Mills, D. Carter, J. K. Greenson, H. A. Oberman, V. Reuter, and M. H. Stoler, Eds., pp.2579-2615, Lippincott Williams and Wilkins, Philadelphia, Pa, USA, 4th edition, 2004.
2. J. L. Powell, D. P. Dulaney, and B. C. Shiro, “Androgen-secreting steroid cell tumor of the ovary”, Southern Medical Journal, Vol.93, no. 7-12, pp. 1201-1204, 2000
3. R. H. Young, P B. Clement, and R. E. Scully, “Sex-cord stromal, steroid cell and germ cell tumours of the ovary”, in Sternberg’s Diagnostic Surgical Pathology, Volume 2, S. E. Mills, D. Carter, J. K. Greenson, V. Reuter, and M. H. Stoler, Eds., pp.2592-2595, Lippincott Williams and Wilkins, Philadelphia, Pa, USA, 5th edition, 2005
4. Hayes MC, Scully RE: Ovarian steroid cell tumours (not otherwise specified): a clinicopathological analysis of 63 cases. Am J Surg Pathol 1987,11:835-845.
5. Scully RE. Stromal luteoma of the ovary. A distinctive type of lipoid cell tumour. Cancer. 1964;17:769-78.
6. Paraskevas M, Scully RE. Hiluscell tumour of the vary. A clinic-pathological analysis of 12 Reinke crystal-positive and nine crystal- negative cases. Int J Gynecol Pathol. 1989;8(4):299-310.
7. Outwater EK, Wagner BJ, Mannion C, McLarney JK, Kim B: Sex cord-stromal and steroid cell tumors of the ovary. Radiographic 1998, 18:1523-1546.
8. Liu AX, Sunj, Song WQ: Steroid cell tumours, not otherwise specified, in an accessory ovary: a case report and literature review. Gynecol Oncol 2005, 97:260-262.
9. Mehdi G Ansari HA, Sherwani RK, Rahman K, Akhtar N. Ovarian Steroid Cell Tumour: Correlation of Histopathology with Clinico-pathologic Features. Pathology Research International.2011;2011:987895 5 pages, 2011.
10. Rabban JT, Zaloudek CJ. A practical approach to immune-histochemical diagnosis of ovarian germ cell tumours and sex cord-stromal tumours. Histopathology. 2013;62:71-88.
2. J. L. Powell, D. P. Dulaney, and B. C. Shiro, “Androgen-secreting steroid cell tumor of the ovary”, Southern Medical Journal, Vol.93, no. 7-12, pp. 1201-1204, 2000
3. R. H. Young, P B. Clement, and R. E. Scully, “Sex-cord stromal, steroid cell and germ cell tumours of the ovary”, in Sternberg’s Diagnostic Surgical Pathology, Volume 2, S. E. Mills, D. Carter, J. K. Greenson, V. Reuter, and M. H. Stoler, Eds., pp.2592-2595, Lippincott Williams and Wilkins, Philadelphia, Pa, USA, 5th edition, 2005
4. Hayes MC, Scully RE: Ovarian steroid cell tumours (not otherwise specified): a clinicopathological analysis of 63 cases. Am J Surg Pathol 1987,11:835-845.
5. Scully RE. Stromal luteoma of the ovary. A distinctive type of lipoid cell tumour. Cancer. 1964;17:769-78.
6. Paraskevas M, Scully RE. Hiluscell tumour of the vary. A clinic-pathological analysis of 12 Reinke crystal-positive and nine crystal- negative cases. Int J Gynecol Pathol. 1989;8(4):299-310.
7. Outwater EK, Wagner BJ, Mannion C, McLarney JK, Kim B: Sex cord-stromal and steroid cell tumors of the ovary. Radiographic 1998, 18:1523-1546.
8. Liu AX, Sunj, Song WQ: Steroid cell tumours, not otherwise specified, in an accessory ovary: a case report and literature review. Gynecol Oncol 2005, 97:260-262.
9. Mehdi G Ansari HA, Sherwani RK, Rahman K, Akhtar N. Ovarian Steroid Cell Tumour: Correlation of Histopathology with Clinico-pathologic Features. Pathology Research International.2011;2011:987895 5 pages, 2011.
10. Rabban JT, Zaloudek CJ. A practical approach to immune-histochemical diagnosis of ovarian germ cell tumours and sex cord-stromal tumours. Histopathology. 2013;62:71-88.
Published
2019-08-26
Issue
Section
Case Report
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access at http://opcit.eprints.org/oacitation-biblio.html).
