Morphological Spectrum of Lesions in Upper Gastrointestinal Endoscopic Biopsies
Keywords:
biopsy, Endoscopy, upper gastrointestinal tract, lesions
Abstract
Background: Gastrointestinal disorders are one of the most common clinically encountered problem. The Spectrum varies significantly due to geographical, dietary and environmental factors. Endoscopic examination along with histopathological biopsy examination is the gold standard for the detection of lesions. Correlation with other clinical data aids in accurate and early diagnosis of lesions. Methods: This descriptive study comprises of 454 endoscopic biopsies of gastrointestinal tract received in the Department of Pathology, Mahatma Gandhi Medical College and Research Institute, Pondicherry over a period of 18 months from December 2016 to May 2018. Brief clinical data, provisional clinical diagnosis, endoscopic findings and histopathological diagnosis were noted. Result: Of the 454 cases examined, 53.9% of patients were males. Highest incidence was recorded in the 41-50 age group comprising of 22.4%. Endoscopic examination showed maximum cases with inflamed mucosa (38.5%). The commonest biopsied site is Gastric antrum. Non-neoplastic lesions were more prevalent (83.4%) than neoplastic lesions. Conclusion: Histopathological evaluation along with details of endoscopic findings aids in providing an accurate diagnosis.References
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2. Kumar V, Abbas AK, Fauston. Robbins and Cotran Pathologic Basis of disease. Chapter 17. Gastrointestinal tract 9th Edition
3. Rashmi K, Karar A, Mangala G. A study on histopathological spectrum of upper gastrointestinal tract endoscopic biopsies. Int J Med Res Health Sci. 2013;2(3):418-24
4. Suvarna KS, Layton C, Bancroft JD, editors. Theory and practice of histological techniques. 7. ed. Edinburgh: Elsevier Churchill Livingston; 2013. 637 p.
5. Islam SMJ, Ahmed ASMM, Ahmad MSU, Hafiz S. Endoscopic and Histologic Diagnosis of Upper Gastrointestinal Lesions, Experience in a Port City of Bangladesh. Chattagram Maa-O-Shishu Hospital Medical College Journal. 2014 Nov 28;13(3):11–4.
6. Hussain SI, Reshi R, Akhter G, Beigh A clinico histopathological study of upper gastrointestinal tract endoscopic biopsies. International Journal of Current Research and Review. 2015;7(16):78–85.
7. Shanmugasamy K, Bhavani K, Anandraj VK, Narasimhan R, Kotasthane DS. Clinical Correlation of Upper Gastrointestinal Endoscopic Biopsies with Histopathological Findings and To Study the Histopathological Profile of Various Neoplastic and Non-Neoplastic Lesions. J Pharm Biomed Sci 2016;06(03):220-224
8. Sheikh BA, Hamdani SM, Malik R. Hisotopatholgic spectrum of lesions of upper gastrointestinal tract - A study of endoscopic biopsies. Glob J Med Public Heal. 2015;4(4):1-8
9. Somani N, Patil P. Histopathological study of the upper gastrointestinal tract endoscopic biopsies. Annals of Pathology and Laboratory Medicine 2018;5(8):683-8.
10. Khandelia R, Saikia M. Histopathological spectrum of upper gastrointestinal tract mucosal biopsies: A Prospective study. International Journal of Medical Science and Clinical Inventions 2017;4(11):3314-16
11. Rani D, Bhuvan S, Gupta A. A study of morphological spectrum of upper gastrointestinal tract lesions by endoscopy and correlation between endoscopic and histopathological findings. Indian J Pathol Oncol 2019;6(1):28-34.
Published
2019-08-02
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