Seroprevalence of HIV Infection in Donated Blood and Its Implications in Safe Blood Practices
Keywords:
Seroprevalence, TTI, voluntary donors, replacement donors
Abstract
Background: Blood transfusion is an integral and indispensible part of treatment in hospitals these days. Transfusion transmissible infections (TTI) are one of the important complications of blood transfusion. This study is aimed at assessing the seroprevalence of HIV among healthy blood donors in our region and its implications on safe blood practices. Materials and methods: This is a retrospective study done over a period of 3 years from August 2015 to July 2018 in two blood banks of Gadag i.e. Gadag Institute of Medical Sciences (GIMS) blood bank and Indian Medical Association (IMA) blood bank. A total of 20,144 blood donors were included in the study. It included both voluntary donors and replacement donors. Donors were screened using donor questionnaire form followed by general physical examination for medical and surgical illness. Eligible blood donors donated blood and their blood samples were subjected to a test that detected the presence of antibodies to HIV by using rapid test kit by Qualpro and then confirmed by 4th generation Qualisa ELISA test kit. Result: In the present study, out of 20,144 blood donors 19,676 (97.67%) were males and 468 (2.33%) were females. Total number of seropositive cases of HIV was 34. The overall seroprevalence was 0.17%. All the seropositive cases were males and the seroprevalence was 0.17%. The prevalence of seropositive cases among voluntary donors was 0.048% and among replacement donors was 0.72%. Conclusion: Seroprevalence of HIV in the region of Gadag is 0.17%.References
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2. Chaudhary V, Agrawal KV, Sexena SK, Upadhyay D, Singh A, Singh PS. Seroprevalence of common transfusion transmissible infections among blood donors in western Uttar Pradesh, India. Int J Med Sci Public Health. 2014;3(11):1381-4
3. India HIV estimations 2017-Technical report. New Delhi:National AIDS Control Organisation and ICMR-National Institute Of Medical Sciences.2018.47p. Available from GOI/NACO/MES/HIV Estimations 2017/100818
4. Zulfiqar HF, Javed A, Sumbal, Afroze B, Ali Q, Akbar K et al. HIV diagnosis and treatment through advanced technologies. Front Public Health. 2017;5:32 Available from: doi 10.3389/fpubh.2017.00032
5. Makroo RN, Chowdhary M, Bhatia A, Arora B, Rosamma NL. Prevalence of HIV among blood donors in a tertiary care centre in north India. Indian J Med Res. 2010;134:950-3
6. Alexander TS. Human immunodeficiency virus diagnostic testing: 30 years of evolution. Clin Vaccine Immunol. 2016;23(4):249-53
7. Shah N, Shah JM, Jhaveri P, Patel K, Shah CK, Shah NR. Seroprevalence of HBV, HCV, HIV and syphilis among blood donors at a tertiary care teaching hospital in Western India. Gujarat Med J 2013;68(2):35 9.
8. Arora D, Arora B, Khetarpal A. Seroprevalence of HIV, HBV, HCV and syphilis in blood donors in Southern Haryana. Indian J Pathol Microbiol. 2010;53:308-9.
9. Das BK, Gayen BK, Aditya S, Chakrovorty SK, Datta PK, Joseph A. Seroprevalence of hepatitis B, hepatitis C and human immunodeficiency virus among healthy voluntary first-time blood donors in Kolkata. Ann Trop Med Public Health. 2011;4(2):86–90.
10. Makroo RN, Salil P, Vashist RP, Shivlal. Trends of HIV infection in the blood donors of Delhi. Indian J Pathol Microbiol 1996;39:139-42.
11. Sharma DC, Jain A, Woike P, Rai S, Tripathi L, Bharat S. Prevalence of HIV infection among blood donors at a tertiary care centre in Gwalior, India. Int Blood Res Review. 2015;4(4):1-8
12. Pallavi P, Ganesh CK, Jayashree K, Manjunath GV. Seroprev¬alence and trends in transfusion transmitted infections among blood donors in a university hospital blood bank: a 5 year study. Indian J Hematol Blood Transfus 2011;27(1):1–6.
13. Chandra T, Kumar A, Gupta A. Prevalence of transfusion trans¬mitted infections in blood donors: an Indian experience. Trop Doct 2009;39:152–4.
14. Sawke N, Sawke GK, Chawla S. Seroprevalence of common transfusion transmitted infections among blood donors at Bhanpur, Bhopal, MP, from 2006–2008. Peoples J Sci Res 2010;3(1):5–7.
Published
2019-08-08
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