Relationship Between ABO blood Group and Carcinoma of Cervix in South Gujarat Women
Keywords:
Cervical cancer, South Gujarat, ABO blood types
Abstract
Introduction: Cervical cancer is one of the leading causes of death from cancer and second most common cancer, next only to breast cancer among women worldwide and is the most common female cancer in developing countries as well. In India, cervical cancer is the most common women related cancer, followed by breast cancer. Several studies have suggested an association between blood type A and cervical dysplasia/cancer. The aim of this study was to document the relationship between cervical cancer and ABO blood group in South Gujarat population. Materials and Method: The present study was an observational descriptive study and was conducted retrospectively among 147 cases of cervical cancer patient admitted in tertiary care hospital, Surat and diagnosed by histopathologically over period of two and half years. Patients personal details were retrieved from Department of pathology and ABO blood group were retrieved from Department of Immunohaematology and blood transfusion. All details were entered in Microsoft excel and analyzed by descriptive statistics. Results: Among 147 cases, maximum cases were found in age group f 30-44 years and showed preponderance of blood group A(31.97%) followed by group B (29.93%), O (27.21%), AB (10.88%). Conclusion: The frequency of types A, B, AB and O in cervical cancer was different to the general healthy population in South Gujarat region.References
1. Angel Justiz Vaillant 1, Patience Bazuaye, Norma McFarlane-Anderson, Monica P Smikle, Horace Fletcher, and Patrick E. Akpaka. Association between ABO Blood Type and Cervical Dysplasia/Carcinoma in Jamaican Women. British Journal of Medicine & Medical Research.2013;3(4):2017-21
2. Satija A. Cervical cancer in India. South Asia Centre for Chronic Disease. Available from: http://sancd.org/ uploads/pdf/cervical_cancer.pdf.
3. Yuzhalin AE, Kutikhin AG. ABO and Rh blood groups in relation to ovarian, endometrial and cervical cancer risk among the population of South-East Siberia. Asian Pac J Cancer Prev. 2012;10:5091-6.
4. Giancarlo Maria Liumbruno, Massimo Franchini. Beyond Immunohaematology: the role of the ABO blood group in human diseases. Blood Transfuse 2013, 11: 491-9 DOI 10.2450/2013, 0152-13.
5. Cui Y, Noguchi H, Kiguchi K, Aoki D, Susumu N, Nozawa S, Kawakami H, Hirano H, Iwamori M. Human cervical epidermal carcinoma-associated intracellular localization of glycosphingolipid with blood group A type 3 chain. Jpn J Cancer Res.1993;84:664- 672
6. Schroder G. Relation between the blood group and carcinoma; studies on 2145 carcinoma patients. Arch Geschwulstforsch.1955; 8:230-40
7. Kaur I, Singh IP, Bhasin MK. Blood groups in relation to cercinoma of cervix uteri. Hum Hered. 1992; 42:324-6
8. Mittal VP. Blood groups and cancer of cervix uteri. J Obstet Gynaecol India.1970; 20: 240-2.
9. Adelusi B. Haemoglobin genotype, ABO blood groups and carcinoma of cervix. J Trop Med Hyg. 1977;80: 152-4.
10. Kruti A. raja, Gopi H. Dobariya, Chirag A. Unagar, Amrish N. Pandya, Jitendra N. Patel, Sangita J. Wadhwani. Frequency and distribution of ABO sand Rh blood groups among blood donors in tertiary care hospital of South Gujarat, India. Int J med Sci. 2016;4(12): 5377- 81
11. K Akhtar, G Mehdi, R Sherwani, L Sofi. Relationship Between Various Cancers And ABO Blood Groups- A Northern India Experience, The Internet Journal of Pathology.2018;6(8):52-56
12. Alexander W (1921). An enquiry into the distribution of the blood groups in patients suffering from malignant diseases. Br J Exp Pathol.1921;2: 66-9.
13. Johannsen EW (1927). A classification of cancer patients according to their blood groups and some investigations concerning iso-heamagglutination. APMIS. 1927;4: 175-97
14. Marinaccio, M., Traversa, A., Carioggia, E., Valentino, L., Coviello, M., Salamanna, S., et al. Blood groups of the ABO system and survival rate in gynecologic tumors. Minerva Ginecologica.1995; 47(3):69-76.
15. Yuzhalin AE, Kutikhin AG. ABO and Rh blood groups in relation to ovarian, endometrial and cervical cancer risk among the population of South-East Siberia. Asian Pac J Cancer Prev. 2012;13(10):5091-6.
16. Sharma G, Choudhary R, Bharti D (2007). Studies Showing the Relationship between ABO Blood Groups and Major Types of Cancers. Asian J Exp Sci.2017;21:129-32.
17. Lee Jun Kai, Kalyani Raju, Harendra Kumar Malligere Lingaiah, Narayanaswamy Mariyappa.Significance of Blood Group and Social Factors in Carcinoma Cervix in a Semi-Urban Population in India Asian Pac J Cancer Prev.2013;14(8), 4811-14
18. Subodh Mitra, Sukdev Mondal, and Arun Basu.The Study of ABO blood groups in cancer of the female genital organs and cancer of the breast. CANCER. 1962;15:39-41
19. D. Rotkin. Are ABO and Rh blood groups associated with cancer of the uterine cervix? Cancer march 1965;18:391-96
20. Tyagi SP, Tiagi GK, Sushila Pradhan (1967). ABO blood grops in relation to cancer cervix. Indian J Med Sci. 1967;21:611-5.
2. Satija A. Cervical cancer in India. South Asia Centre for Chronic Disease. Available from: http://sancd.org/ uploads/pdf/cervical_cancer.pdf.
3. Yuzhalin AE, Kutikhin AG. ABO and Rh blood groups in relation to ovarian, endometrial and cervical cancer risk among the population of South-East Siberia. Asian Pac J Cancer Prev. 2012;10:5091-6.
4. Giancarlo Maria Liumbruno, Massimo Franchini. Beyond Immunohaematology: the role of the ABO blood group in human diseases. Blood Transfuse 2013, 11: 491-9 DOI 10.2450/2013, 0152-13.
5. Cui Y, Noguchi H, Kiguchi K, Aoki D, Susumu N, Nozawa S, Kawakami H, Hirano H, Iwamori M. Human cervical epidermal carcinoma-associated intracellular localization of glycosphingolipid with blood group A type 3 chain. Jpn J Cancer Res.1993;84:664- 672
6. Schroder G. Relation between the blood group and carcinoma; studies on 2145 carcinoma patients. Arch Geschwulstforsch.1955; 8:230-40
7. Kaur I, Singh IP, Bhasin MK. Blood groups in relation to cercinoma of cervix uteri. Hum Hered. 1992; 42:324-6
8. Mittal VP. Blood groups and cancer of cervix uteri. J Obstet Gynaecol India.1970; 20: 240-2.
9. Adelusi B. Haemoglobin genotype, ABO blood groups and carcinoma of cervix. J Trop Med Hyg. 1977;80: 152-4.
10. Kruti A. raja, Gopi H. Dobariya, Chirag A. Unagar, Amrish N. Pandya, Jitendra N. Patel, Sangita J. Wadhwani. Frequency and distribution of ABO sand Rh blood groups among blood donors in tertiary care hospital of South Gujarat, India. Int J med Sci. 2016;4(12): 5377- 81
11. K Akhtar, G Mehdi, R Sherwani, L Sofi. Relationship Between Various Cancers And ABO Blood Groups- A Northern India Experience, The Internet Journal of Pathology.2018;6(8):52-56
12. Alexander W (1921). An enquiry into the distribution of the blood groups in patients suffering from malignant diseases. Br J Exp Pathol.1921;2: 66-9.
13. Johannsen EW (1927). A classification of cancer patients according to their blood groups and some investigations concerning iso-heamagglutination. APMIS. 1927;4: 175-97
14. Marinaccio, M., Traversa, A., Carioggia, E., Valentino, L., Coviello, M., Salamanna, S., et al. Blood groups of the ABO system and survival rate in gynecologic tumors. Minerva Ginecologica.1995; 47(3):69-76.
15. Yuzhalin AE, Kutikhin AG. ABO and Rh blood groups in relation to ovarian, endometrial and cervical cancer risk among the population of South-East Siberia. Asian Pac J Cancer Prev. 2012;13(10):5091-6.
16. Sharma G, Choudhary R, Bharti D (2007). Studies Showing the Relationship between ABO Blood Groups and Major Types of Cancers. Asian J Exp Sci.2017;21:129-32.
17. Lee Jun Kai, Kalyani Raju, Harendra Kumar Malligere Lingaiah, Narayanaswamy Mariyappa.Significance of Blood Group and Social Factors in Carcinoma Cervix in a Semi-Urban Population in India Asian Pac J Cancer Prev.2013;14(8), 4811-14
18. Subodh Mitra, Sukdev Mondal, and Arun Basu.The Study of ABO blood groups in cancer of the female genital organs and cancer of the breast. CANCER. 1962;15:39-41
19. D. Rotkin. Are ABO and Rh blood groups associated with cancer of the uterine cervix? Cancer march 1965;18:391-96
20. Tyagi SP, Tiagi GK, Sushila Pradhan (1967). ABO blood grops in relation to cancer cervix. Indian J Med Sci. 1967;21:611-5.
Published
02-04-2020
Issue
Section
Original Article
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access at http://opcit.eprints.org/oacitation-biblio.html).
